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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ar
androgen receptor
MGI:88064
84 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Amhtm1Bhr/Amhtm1Bhr
ArTfm/Y
either: (involves: 129P3/J * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6) 		abnormal male reproductive system morphology J:21396
abnormal secondary sex determination J:21396
absent epididymis J:21396
absent vas deferens J:21396
arrest of spermatogenesis J:21396
cryptorchism J:21396
male pseudohermaphroditism J:21396
secondary sex reversal J:21396
ArTfm/Ar+
EdaTa-25H/Eda+
involves: 101/H * C3H/HeH 		abnormal coat/hair pigmentation J:11266
abnormal cranium size J:11266
decreased body size J:11266
domed cranium J:11266
exencephaly J:11266
irregular coat pigmentation J:11266
neonatal lethality, incomplete penetrance J:11266
polydactyly J:11266
prenatal lethality, incomplete penetrance J:11266
striated fur J:11266
supernumerary incisors J:11266
syndactyly J:11266
transverse fur striping J:11266
ArTfm/Ar+
Lactb2Tg(Igh-Meis1)2770Amb/Lactb2Tg(Igh-Meis1)2770Amb
involves: FVB/NJ 		normal mortality/aging J:79618
ArTfmEdaTa-25H/Y
involves: 101/H * C3H/HeH 		abnormal coat/hair pigmentation J:11266
decreased body size J:11266
exencephaly J:11266
irregular coat pigmentation J:11266
male pseudohermaphroditism J:11266
neonatal lethality, incomplete penetrance J:11266
prenatal lethality, incomplete penetrance J:11266
striated fur J:11266
transverse fur striping J:11266
ArTfm/Y
Insl3tm1Imad/Insl3tm1Imad
involves: 129/Sv * CD-1 * STOCK EdaTa 		abnormal female reproductive system morphology J:83429
abnormal gubernaculum morphology J:83429
abnormal male reproductive system morphology J:83429
abnormal secondary sex determination J:83429
absent epididymis J:83429
absent vas deferens J:83429
bilateral cryptorchism J:83429
male pseudohermaphroditism J:83429
ArTfm/Y
Tg(TSPY)9Jshm/0
involves: NMRI * STOCK EdaTa Atp7aMo-blo 		abnormal seminiferous tubule morphology J:140803
arrest of male meiosis J:140803
cryptorchism J:140803
enlarged seminiferous tubules J:140803
increased Leydig cell number J:140803
increased testis tumor incidence J:140803
increased testis weight J:140803
secondary sex reversal J:140803
Artm1(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J 		increased body weight J:108849
increased percent body fat/body weight J:108849
Artm1(AR)Dmr/Y
Tg(TRAMP)8247Ng/0
involves: 129S1/Sv * C57BL/6 		increased prostate gland tumor incidence J:108849
Artm1Verh/Y
Ptentm1Hwu/Ptentm1Hwu
Tg(Pbsn-cre)4Prb/0
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * DBA/2 		increased prostate gland adenocarcinoma incidence J:172730
Artm2(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J 		normal reproductive system phenotype J:104360
Artm2(AR)Dmr/Y
Tg(TRAMP)8247Ng/0
involves: 129S1/Sv * C57BL/6 		increased prostate gland tumor incidence J:108849
Artm3(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J 		normal behavior/neurological phenotype J:114552
normal growth/size/body region phenotype J:114552
increased body weight J:108849
increased percent body fat/body weight J:108849
normal muscle phenotype J:114552
normal nervous system phenotype J:114552
normal reproductive system phenotype J:104360
Artm3(AR)Dmr/Y
Tg(TRAMP)8247Ng/0
involves: 129S1/Sv * C57BL/6 		decreased tumor incidence J:108849
Artm3.1(AR)Ska/Y
involves: C57BL/6 * C57BL/6J * CBA 		decreased prostate gland weight J:170092
increased circulating testosterone level J:170092
reduced fertility J:170092
small prostate gland J:170092
small seminiferous tubules J:170092
Artm3.1(AR)Ska/Y
Tg(KLKB1-cre/ERT2)1Pcn/0
involves: C57BL/6 * C57BL/6J * CBA 		abnormal prostate gland physiology J:170092
increased circulating testosterone level J:170092
increased prostate gland ventral lobe weight J:170092
increased prostate gland weight J:170092
reduced fertility J:170092
Artm3.1(AR)Ska/Y
Tg(KLKB1-cre/ERT2)1Pcn/0
Tg(TRAMP)8247Ng/0
involves: C57BL/6 * C57BL/6J * CBA 		abnormal tumor morphology J:170092
decreased tumor latency J:170092
increased prostate gland tumor incidence J:170092
increased tumor growth/size J:170092
premature death J:170092
Artm4(AR)Dmr/Y
involves: 129S1/Sv * C57BL/6J 		abnormal blood homeostasis J:114552
abnormal cell cytoskeleton morphology J:104360
abnormal muscle electrophysiology J:114552
abnormal seminiferous tubule morphology J:114552
abnormal Sertoli cell morphology J:104360
abnormal skeletal muscle fiber morphology J:114552
abnormal spermatogenesis J:104360
abnormal spinal cord morphology J:114552
abnormal testis morphology J:104360
centrally nucleated skeletal muscle fibers J:114552
decreased body size J:114552
decreased body weight J:114552
decreased circulating follicle stimulating hormone level J:104360
decreased circulating testosterone level J:114552
decreased grip strength J:114552
decreased testis weight J:104360
decreased urine major urinary protein level J:104360
distended urinary bladder J:114552
impaired muscle relaxation J:114552
increased blood urea nitrogen level J:114552
increased circulating creatinine level J:114552
increased circulating luteinizing hormone level J:104360
increased circulating potassium level J:114552
increased variability of skeletal muscle fiber size J:114552
motor neuron degeneration J:114552
muscle weakness J:114552
myopathy J:114552
oligozoospermia J:104360
premature death J:114552
progressive muscle weakness J:114552
reduced male fertility J:104360, J:114552
skeletal muscle fiber atrophy J:114552
testicular atrophy J:104360, J:114552
Artm4(AR)Dmr/Ar+
involves: 129S1/Sv * C57BL/6J 		decreased grip strength J:114552
normal growth/size/body region phenotype J:114552
increased circulating testosterone level J:114552
increased urine major urinary protein level J:114552
normal mortality/aging J:114552
muscle weakness J:114552
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
MGI 6.24 		The Jackson Laboratory