Arnt Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Arnt
aryl hydrocarbon receptor nuclear translocator
MGI:88071

50 phenotypes from 7 alleles in 12 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Arnt^em1(IMPC)H/Arnt^em1(IMPC)H C57BL/6N-Arnt^em1(IMPC)H/H	preweaning lethality, complete penetrance	J:211773
Arnt^tm1.1Gonz/Arnt^tm1.1Gonz Tg(Vil1-cre)20Syr/0 involves: 129X1/SvJ * C57BL/6 * DBA/2	decreased circulating iron level	J:189504
	decreased erythrocyte cell number	J:189504
	decreased hematocrit	J:189504
	decreased hemoglobin content	J:189504
Arnt^tm1.1Gonz/Arnt^tm1.2Gonz Tg(KRT5-cre)1Tak/0 involves: 129X1/SvJ * C3H * C57BL/6	abnormal epidermis stratum corneum morphology	J:86533
	abnormal skin physiology	J:86533
	decreased keratohyalin granule number	J:86533
	dehydration	J:85934, J:86533
	normal homeostasis/metabolism phenotype	J:85934
	impaired skin barrier function	J:86533
	increased keratinocyte apoptosis	J:86533
	neonatal lethality, complete penetrance	J:85934, J:86533
	weight loss	J:86533
Arnt^tm1.1Gonz/Arnt^tm1.2Gonz Tg(Lck-cre)I57Jxm/0 involves: 129X1/SvJ * ICR	abnormal immune system physiology	J:85934
	decreased physiological sensitivity to xenobiotic	J:85934
Arnt^tm1Bra/Arnt^tm1Bra B6.129-Arnt^tm1Bra	decreased physiological sensitivity to xenobiotic	J:89470
	female infertility	J:89470
	prenatal lethality, incomplete penetrance	J:89470
Arnt^tm1Bra/Arnt^tm1Bra involves: 129	patent ductus venosus	J:94465
Arnt^tm1Gonz/Arnt^tm1Gonz involves: 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:64967
Arnt^tm1Gonz/Arnt^tm1Gonz Tg(MMTV-cre)1Mam/0 involves: 129X1/SvJ * FVB	abnormal lactation	J:76280
	abnormal mammary gland growth during pregnancy	J:76280
	abnormal ovarian follicle morphology	J:76280
	decreased litter size	J:76280
	decreased primordial ovarian follicle number	J:76280
Arnt^tm1Gonz/Arnt^tm1Gonz Tg(Mx1-cre)1Cgn/0 involves: 129X1/SvJ * C57BL/6 * CBA	decreased physiological sensitivity to xenobiotic	J:64967
Arnt^tm1Gonz/Arnt^tm1Gonz Tg(Wap-cre)11738Mam/0 involves: 129X1/SvJ * C57BL/6 * SJL	normal reproductive system phenotype	J:76280
Arnt^tm1Mcs/Arnt^tm1Mcs involves: 129S1/Sv * 129X1/SvJ	abnormal angiogenesis	J:39730
	abnormal chorionic plate morphology	J:66515
	abnormal placenta development	J:66515
	abnormal spongiotrophoblast layer morphology	J:66515
	abnormal trophoblast giant cell morphology	J:66515
	abnormal trophoblast layer morphology	J:66515
	abnormal visceral yolk sac morphology	J:39730
	absent placental labyrinth	J:66515
	absent vitelline blood vessels	J:39730
	normal cardiovascular system phenotype	J:39730
	normal cellular phenotype	J:39730, J:66515
	decreased embryo size	J:39730
	disorganized yolk sac vascular plexus	J:39730
	embryonic growth retardation	J:39730
	embryonic lethality, complete penetrance	J:39730
	impaired hematopoiesis	J:70037
Arnt^tm1Oha/Arnt⁺ involves: 129X1/SvJ * C57BL/6J	no abnormal phenotype detected	J:44365
Arnt^tm1Oha/Arnt^tm1Oha involves: 129X1/SvJ * C57BL/6J	abnormal neural tube morphology	J:44365
	abnormal placenta morphology	J:44365
	abnormal placenta vasculature	J:44365
	delayed embryo turning	J:44365
	embryonic growth retardation	J:44365
	embryonic lethality during organogenesis, complete penetrance	J:44365
	forebrain hypoplasia	J:44365
	placenta hemorrhage	J:44365
	shortened head	J:44365

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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