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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Atf4
activating transcription factor 4
MGI:88096
14 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Atf4tm1Jml/Atf4tm1Jml
Trp53tm1Brd/Trp53tm1Brd
involves: 129S7/SvEvBrd * 129X1/SvJ 		abnormal lens fiber morphology J:62578
abnormal lens morphology J:62578
normal vision/eye phenotype J:62578
Atf4tm1Kry/Atf4tm1Kry
Creb1tm3Gsc/Creb1tm3Gsc
Tg(Col1a1-cre)1Kry/0
involves: 129P2/OlaHsd * C57BL/6J * FVB 		normal homeostasis/metabolism phenotype J:152695
Atf4tm1Tow/Atf4+
Ptprvtm1Asmi/Ptprv+
either: (involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J * NIH Black Swiss) or (involves: 129P2/OlaHsd * C57BL/6J * NIH Black Swiss) 		decreased circulating glucose level J:152695
increased circulating insulin level J:152695
increased pancreatic beta cell proliferation J:152695
Atf4tm1Tow/Atf4+
Satb2tm1Rug/Satb2+
either: (involves: 129P2/OlaHsd * NIH Black Swiss) or (involves: 129S1/Sv * 129X1/SvJ * NIH Black Swiss) 		abnormal bone structure J:115876
decreased bone ossification J:115876
decreased bone trabecula number J:115876
decreased bone volume J:115876
Atf4tm1Tow/Atf4tm1Tow
Hivep3tm1Glm/Hivep3tm1Glm
involves: 129 * C57BL/6 		increased bone ossification J:201597
increased bone volume J:201597
increased trabecular bone thickness J:201597
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory