About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
MGI:88108
36 phenotypes from 3 alleles in 6 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Aqp5tm1.1(cre)Pfl/?
Atp1b1tm1.1Zboro/Atp1b1tm1.1Zboro
129S-Atp1b1tm1.1Zboro Aqp5tm1.1(cre)Pfl 		impaired pulmonary alveolar fluid clearance J:233742
normal respiratory system phenotype J:233742
Atp1b1em1(IMPC)Mbp/Atp1b1+
C57BL/6NCrl-Atp1b1em1(IMPC)Mbp/MbpMmucd 		abnormal retina morphology J:211773
abnormal skin morphology J:211773
abnormal testis morphology J:211773
abnormal vitreous body morphology J:211773
cataract J:211773
decreased locomotor activity J:211773
enlarged testis J:211773
eye hemorrhage J:211773
increased startle reflex J:211773
persistence of hyaloid vascular system J:211773
shortened QRS complex duration J:211773
Atp1b1em1(IMPC)Mbp/Atp1b1em1(IMPC)Mbp
C57BL/6NCrl-Atp1b1em1(IMPC)Mbp/MbpMmucd 		abnormal embryo turning J:211773
abnormal heart morphology J:211773
abnormal neural tube closure J:211773
abnormal neural tube morphology J:211773
abnormal optic vesicle formation J:211773
abnormal pharyngeal arch morphology J:211773
abnormal somite shape J:211773
abnormal visceral yolk sac morphology J:211773
abnormal vitelline vasculature morphology J:211773
embryonic growth retardation J:211773
prenatal lethality prior to heart atrial septation J:211773
preweaning lethality, complete penetrance J:211773
Atp1b1tm1.1Akra/Atp1b1tm1.1Akra
involves: 129S/SvEv 		no abnormal phenotype detected J:152596
Atp1b1tm1.1Akra/Atp1b1tm1.1Akra
Myl2tm1(cre)Krc/Myl2+
involves: 129S/SvEv * 129S4/SvJae 		abnormal cardiac muscle contractility J:152596
abnormal myocardial fiber physiology J:152596
cardiac hypertrophy J:152596
decreased heart ventricle muscle contractility J:152596
decreased physiological sensitivity to xenobiotic J:152596
increased heart weight J:152596
increased response of heart to induced stress J:152596
increased susceptibility to induced morbidity/mortality J:152596
Atp1b1tm1.1Zboro/Atp1b1tm1.1Zboro
Tg(Nkx2-1-cre)2Sand/0
involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 		postnatal lethality, complete penetrance J:233742
Atp1b1tm1.1Zboro/Atp1b1tm1.1Zboro
Tg(Sftpc-cre)1Blh/0
involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * DBA/2 		abnormal respiratory epithelial sodium ion transmembrane transport J:233742
impaired pulmonary alveolar fluid clearance J:233742
normal respiratory system phenotype J:233742
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory