Bcl2l1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Bcl2l1
BCL2-like 1
MGI:88139

20 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Bak1^tm1Thsn/Bak1⁺ Bcl2l1^tm1Dlo/Bcl2l1⁺ B6.Cg-Bcl2l1^tm1Dlo Bak1^tm1Thsn	abnormal platelet morphology	J:149205
Bak1^tm1Thsn/Bak1⁺ Bcl2l1^Plt20/Bcl2l1⁺ involves: 129 * BALB/c * C57BL/6	abnormal platelet morphology	J:149205
Bak1^tm1Thsn/Bak1^tm1Thsn Bax^tm1Sjk/Bax^tm2Sjk Bcl2l1^tm1.1Mam/Bcl2l1^tm1.1Mam Tg(MMTV-cre)#Mam/0 involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * FVB	normal hematopoietic system phenotype	J:141545
Bak1^tm1Thsn/Bak1^tm1Thsn Bcl2l1^tm1Dlo/Bcl2l1⁺ B6.Cg-Bcl2l1^tm1Dlo Bak1^tm1Thsn	abnormal platelet physiology	J:149205
	thrombocytosis	J:149205
Bax^tm1Dlo/Bax^tm1Dlo Bcl2l1^tm1Dlo/Bcl2l1^tm1Dlo involves: 129P2/OlaHsd	decreased neuron apoptosis	J:39573
	prenatal lethality, complete penetrance	J:39573
Bax^tm1Sjk/Bax⁺ Bcl2l1^tm1Mam/Bcl2l1^tm1Mam involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6	abnormal ovarian folliculogenesis	J:63161
	decreased male germ cell number	J:63161
	male infertility	J:63161
Bax^tm1Sjk/Bax^tm1Sjk Bcl2l1^tm1Mam/Bcl2l1^tm1Mam involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6	abnormal ovarian folliculogenesis	J:63161
	abnormal spermatogenesis	J:63161
	azoospermia	J:63161
	male infertility	J:63161
Bcl2l1^tm1.1Mam/Bcl2l1^tm1.1Mam Tg(Ins2-cre)25Mgn/0 Tg(RIP1-Tag)2Dh/0 involves: 129S6/SvEvTac * C57BL/6 * DBA	increased pancreas tumor incidence	J:146436
Bcl2l1^tm1.1Mam/Bcl2l1^tm1.1Mam Tg(RIP1-Tag)2Dh/0 involves: 129S6/SvEvTac * C57BL/6 * DBA	increased pancreas tumor incidence	J:146436
Bcl2l1^tm1Dlo/Bcl2l1^tm1Dlo Casp9^tm1Flv/? involves: 129S1/Sv * C57BL/6	increased apoptosis	J:66953
	increased neuron apoptosis	J:66953
Bcl2l1^tm1Dlo/Bcl2l1^tm1Dlo Casp9^tm1Flv/Casp9^tm1Flv involves: 129S1/Sv * C57BL/6	abnormal telencephalon development	J:66953
	decreased apoptosis	J:66953
	exencephaly	J:66953
	increased apoptosis	J:66953
Bcl2l1^tm1Ywh/Bcl2l1^tm1Ywh Mcl1^tm1Ywh/Mcl1^tm1Ywh Tg(Cd4-cre)1Cwi/0 involves: 129S6/SvEvTac * C57BL/6 * DBA/2	absent CD4-positive, alpha-beta T cells	J:137400
	absent CD8-positive, alpha-beta T cells	J:137400
	decreased double-positive T cell number	J:137400

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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