About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Bglap
bone gamma carboxyglutamate protein
MGI:88156
38 phenotypes from 2 alleles in 4 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Bglap/Bglap2tm1Kry/Bglap/Bglap2tm1Kry
involves: 129S7/SvEvBrd 		abnormal fat cell morphology J:126780
abnormal glucose homeostasis J:126780
abnormal pancreatic islet morphology J:126780
abnormal seminiferous tubule epithelium morphology J:170888
abnormal spermatid morphology J:170888
abnormal spermatocyte morphology J:170888
decreased adipocyte glucose uptake J:126780
decreased circulating insulin level J:126780
decreased circulating testosterone level J:170888
decreased energy expenditure J:126780
decreased epididymis weight J:170888
decreased insulin secretion J:126780
decreased Leydig cell number J:170888
decreased pancreatic beta cell mass J:126780
decreased pancreatic beta cell proliferation J:126780
decreased pancreatic islet number J:126780
decreased seminal vesicle weight J:170888
decreased testis weight J:170888
impaired glucose tolerance J:126780
increased circulating estradiol level J:170888
increased circulating glucose level J:126780
increased circulating luteinizing hormone level J:170888
increased circulating triglyceride level J:126780
increased total body fat amount J:126780
insulin resistance J:126780
oligozoospermia J:170888
normal reproductive system phenotype J:170888
small pancreatic islets J:126780
small testis J:170888
Bglap/Bglap2tm1Kry/Bglap/Bglap2tm1Kry
involves: 129S7/SvEvBrd * C57BL/6 		abnormal bone remodeling J:34440
abnormal bone structure J:34440
abnormal long bone diaphysis morphology J:34440
abnormal skeleton development J:34440
increased bone mass J:34440
increased bone strength J:34440
increased compact bone thickness J:34440
increased osteoclast cell number J:34440
increased trabecular bone thickness J:34440
Bglap/Bglap2tm3.1Kry/Bglap/Bglap2tm3.1Kry
Tg(Col1a1-cre)1Kry/0
involves: FVB 		decreased circulating testosterone level J:170888
decreased epididymis weight J:170888
decreased seminal vesicle weight J:170888
decreased testis weight J:170888
oligozoospermia J:170888
small testis J:170888
Bglap/Bglap2tm3.1Kry/Bglap/Bglap2tm3.1Kry
Tg(Cyp17a1-icre)AJako/0
involves: C57BL/6 * SJL 		normal reproductive system phenotype J:170888
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory