C5ar1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

C5ar1
complement component 5a receptor 1
MGI:88232

12 phenotypes from 3 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
C5ar1^tm1Cge/C5ar1^tm1Cge B6.129S4(Cg)-C5ar1^tm1Cge	abnormal c-wave shape	J:214214
C5ar1^tm1Cge/C5ar1^tm1Cge B6.129S4(Cg)-C5ar1^tm1Cge	decreased circulating free fatty acids level	J:214214
C5ar1^tm1Cge/C5ar1^tm1Cge involves: 129S4/SvJae	abnormal humoral immune response	J:35529
	impaired neutrophil recruitment	J:69177
	increased susceptibility to bacterial infection	J:69177
	increased susceptibility to induced morbidity/mortality	J:69177
C5ar1^tm1Cge/C5ar1^tm1Cge involves: 129S4/SvJae * C57BL/6	decreased circulating interleukin-6 level	J:166640
C5ar1^tm1Cge/C5ar1^tm1Cge involves: 129S4/SvJae * C57BL/6	decreased osteoclast cell number	J:166640
C5ar1^tm1Raw/C5ar1^tm1Raw B6.Cg-C5ar1^tm1Raw	normal immune system phenotype	J:139786
C5ar1^tm1Raw/C5ar1^tm1Raw B6.Cg-C5ar1^tm1Raw	increased spleen germinal center number	J:139786
C5ar1^tm1Raw/C5ar1^tm1Raw involves: C57BL/6J	normal reproductive system phenotype	J:86845
C5ar1^tm1Song/C5ar1^tm1Song involves: 129S6/SvEvTac * C57BL/6	abnormal neutrophil physiology	J:184056

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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