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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Calr
calreticulin
MGI:88252
51 phenotypes from 5 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Calrtm1.1Osb/Calrtm1.1Osb
involves: 129S2/SvPas 		abnormal fibroblast physiology J:250114
Calrtm1.2Osb/Calrtm1.1Osb
Tg(Stra8-cre)1Osb/0
involves: 129S2/SvPas 		normal reproductive system phenotype J:250114
Calrtm1.2Osb/Calrtm1.1Osb
Tg(Zp3-cre)93Knw/0
involves: 129S2/SvPas * C57BL/6J 		abnormal oocyte morphology J:250114
abnormal ovarian follicle morphology J:250114
decreased corpora lutea number J:250114
decreased cumulus expansion J:250114
decreased fertilization frequency J:250114
decreased granulosa cell proliferation J:250114
decreased litter size J:250114
decreased mature ovarian follicle number J:250114
decreased ovary weight J:250114
decreased superovulation rate J:250114
impaired ovarian folliculogenesis J:250114
increased tertiary ovarian follicle number J:250114
reduced female fertility J:250114
Calrtm1Mlk/Calrtm1Mlk
involves: 129S4/SvJae * C57BL/6J 		abnormal calcium ion homeostasis J:53466
abnormal intercalated disk morphology J:119647
abnormal myocardial fiber morphology J:119647
abnormal sarcomere morphology J:119647
abnormal Z line morphology J:119647
decreased myocardial fiber number J:119647
increased cardiac muscle glycogen level J:119647
lethality throughout fetal growth and development, incomplete penetrance J:53466
omphalocele J:53466
small heart J:119647
thin myocardium compact layer J:53466
thin ventricular wall J:53466, J:119647
trabecula carnea hypoplasia J:53466, J:119647
Calrtm1Star/Calrtm1Star
either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL) 		abnormal cell adhesion J:73539
abnormal cell migration J:61550
abnormal cell physiology J:61550
abnormal interventricular septum muscular part morphology J:61550
exencephaly J:61550
failure of ventral body wall closure J:61550
incomplete rostral neuropore closure J:61550
increased cardiomyocyte apoptosis J:61550
lethality throughout fetal growth and development, complete penetrance J:61550
omphalocele J:61550
thin ventricular wall J:61550
trabecula carnea hypoplasia J:61550
ventricular cardiomyopathy J:61550
Tg(CAG-Calr)#Mlk/0
Tg(Myh6-cre/Esr1*)1Liao/0
involves: C57BL/6 		abnormal heart echocardiography feature J:199413
abnormal heart electrocardiography waveform feature J:199413
abnormal P wave J:199413
abnormal T wave J:199413
cardiac interstitial fibrosis J:253065
congestive heart failure J:199413
decreased body weight J:199413
decreased cardiac muscle contractility J:199413
decreased QRS amplitude J:199413
dilated cardiomyopathy J:199413
dilated heart left ventricle J:199413
enlarged heart J:199413
prolonged PR interval J:199413
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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07/05/2024
MGI 6.24 		The Jackson Laboratory