Camk2b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Camk2b
calcium/calmodulin-dependent protein kinase II, beta
MGI:88257

26 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Camk2b^tm1.1Ics/Camk2b⁺ B6J.129S2(Cg)-Camk2b^tm1.1Ics	normal behavior/neurological phenotype	J:219040
	decreased anxiety-related response	J:219040
	normal homeostasis/metabolism phenotype	J:219040
	increased percent body fat/body weight	J:219040
Camk2b^tm1.1Ics/Camk2b^tm1.1Ics B6J.129S2(Cg)-Camk2b^tm1.1Ics	abnormal nest building behavior	J:219040
	abnormal object recognition memory	J:219040
	abnormal voluntary movement	J:219040
	ataxia	J:219040
	normal behavior/neurological phenotype	J:219040
	decreased anxiety-related response	J:219040
	decreased body size	J:219040
	decreased grip strength	J:219040
	normal homeostasis/metabolism phenotype	J:219040
	impaired balance	J:219040
	impaired coordination	J:219040
	increased percent body fat/body weight	J:219040
	slow postnatal weight gain	J:219040
Camk2b^tm1.1Ksak/Camk2b^tm1.1Ksak involves: C57BL/6N	normal nervous system phenotype	J:186178
Camk2b^{tm1b(EUCOMM)Hmgu}/Camk2b⁺ C57BL/6N-Camk2b^{tm1b(EUCOMM)Hmgu}/Ieg	abnormal behavior	J:211773
	decreased prepulse inhibition	J:211773
	decreased thigmotaxis	J:211773
	decreased vertical activity	J:211773
	hyperactivity	J:211773
	improved glucose tolerance	J:211773
Camk2b^{tm1b(EUCOMM)Hmgu}/Camk2b^{tm1b(EUCOMM)Hmgu} C57BL/6N-Camk2b^{tm1b(EUCOMM)Hmgu}/Ieg	preweaning lethality, incomplete penetrance	J:211773
Camk2b^tm1Yelg/Camk2b^tm1Yelg involves: 129P2/OlaHsd	impaired contextual conditioning behavior	J:174521
	normal nervous system phenotype	J:174521
	reduced long-term potentiation	J:174521
Camk2b^tm1Yelg/Camk2b^tm1Yelg involves: 129P2/OlaHsd * C57BL/6	abnormal long-term depression	J:152575
	abnormal long-term potentiation	J:152575
	abnormal synaptic plasticity	J:152575
	ataxia	J:152575
	impaired coordination	J:152575
	normal nervous system phenotype	J:152575
Camk2b^tm2.1Yelg/Camk2b^tm2.1Yelg involves: 129P2/OlaHsd * C57BL/6	normal behavior/neurological phenotype	J:174521
	normal nervous system phenotype	J:174521

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24