Capns1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Capns1
calpain, small subunit 1
MGI:88266

19 phenotypes from 6 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Capns1^tm1.1Otsu/Capns1^tm1.1Otsu Tg(Myh6-cre)2182Mds/0 involves: C57BL/6J * FVB/N	abnormal heart left ventricle morphology	J:176736
	abnormal myocardial fiber physiology	J:176736
	cardiac fibrosis	J:176736
	congestive heart failure	J:176736
	decreased cardiac muscle contractility	J:176736
	dilated heart left ventricle	J:176736
	increased lung weight	J:176736
	increased response of heart to induced stress	J:176736
Capns1^tm1Kraj/Capns1^tm1Kraj involves: FVB/N	embryonic lethality during organogenesis	J:94077
Capns1^tm1Pag/Capns1^tm1Pag involves: 129S1/Sv * 129X1/SvJ * CD-1	abnormal heart development	J:74966
	abnormal neural crest cell migration	J:74966
	abnormal sinus venosus morphology	J:74966
	abnormal vasculogenesis	J:74966
	abnormal vitelline vasculature morphology	J:74966
	embryonic lethality during organogenesis, complete penetrance	J:74966
	hemorrhage	J:74966
	increased nucleated erythrocyte cell number	J:74966
Capns1^tm1Ujz/Capns1^tm1Ujz involves: 129X1/SvJ * C57BL/6	embryonic lethality, complete penetrance	J:110464
Capns1^tm2.1Pag/Capns1^tm2.1Pag involves: 129P2/OlaHsd * C57BL/6 * SJL	embryonic lethality during organogenesis, incomplete penetrance	J:110138
Capns1^tm2Pag/Capns1^tm2.1Pag Tg(CMV-cre)1Ipc/0 involves: 129P2/OlaHsd * C57BL/6 * SJL	embryonic lethality during organogenesis, incomplete penetrance	J:110138

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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