Ccnd1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ccnd1
cyclin D1
MGI:88313

38 phenotypes from 11 alleles in 14 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ccnd1^{tm1(CCNE)Pisc}/Ccnd1^{tm1(CCNE)Pisc} involves: 129/Sv * C57BL/6	abnormal eye electrophysiology	J:55690
	abnormal mammary gland growth during pregnancy	J:55690
	abnormal retina morphology	J:55690
	normal behavior/neurological phenotype	J:55690
	normal growth/size/body region phenotype	J:55690
	normal mortality/aging	J:55690
Ccnd1^tm1Dsn/Ccnd1^tm1Dsn involves: 129P2/OlaHsd	decreased total retina thickness	J:83530
Ccnd1^tm1Dsn/Ccnd1^tm1Dsn involves: 129P2/OlaHsd * C57BL/6J	abnormal mammary gland growth during lactation	J:29258
	abnormal mammary gland growth during pregnancy	J:29258
	abnormal mandible morphology	J:29258
	abnormal maxilla morphology	J:29258
	normal cellular phenotype	J:29258
	decreased body size	J:29258
	disorganized retina ganglion layer	J:29258
	disorganized retina layers	J:29258
	lactation failure	J:29258
	limb grasping	J:29258
	long incisors	J:29258
	misaligned incisors	J:29258
	postnatal lethality, incomplete penetrance	J:66707
	prenatal lethality, incomplete penetrance	J:29258
	pup cannibalization	J:29258
	retina hypoplasia	J:29258
	thin retina ganglion layer	J:29258
Ccnd1^tm1Phin/Ccnd1^tm1Phin involves: 129S4/SvJae * C57BL/6	abnormal eye electrophysiology	J:105045
	abnormal retina morphology	J:105045
	limb grasping	J:105045
	postnatal growth retardation	J:105045
	normal reproductive system phenotype	J:105045
Ccnd1^tm1Wbg/Ccnd1^tm1Wbg involves: 129S2/SvPas	abnormal eye electrophysiology	J:95994, J:105045
	abnormal mammary gland growth during pregnancy	J:95994
	lactation failure	J:95994
	limb grasping	J:95994
	postnatal growth retardation	J:95994, J:105045
	postnatal lethality, incomplete penetrance	J:105045
	retina hypoplasia	J:95994, J:105045
Ccnd1^tm1Wbg/Ccnd1^tm1Wbg involves: 129S2/SvPas * C57BL/6	abnormal eye electrophysiology	J:55690
	abnormal mammary gland growth during pregnancy	J:55690
	limb grasping	J:55690
	postnatal growth retardation	J:55690
	retina hypoplasia	J:55690
Ccnd1^tm1Wbg/Ccnd1^tm1Wbg involves: 129S2/SvPas * CD-1	abnormal digestive system physiology	J:157019
Ccnd1^tm1Wbg/Ccnd1^tm1Wbg involves: 129S2/SvPas * FVB/N	abnormal nursing	J:178842
Ccnd1^tm1Wbg/Ccnd1^tm1Wbg involves: 129S2/SvPas * FVB/N	normal endocrine/exocrine gland phenotype	J:178842
Ccnd1^tm1Wbg/Ccnd1^tm5.1Pisc involves: 129S2/SvPas	no abnormal phenotype detected	J:192032
Ccnd1^tm1Wbg/Ccnd1^tm5.1Pisc Tg(CAG-cre/Esr1)5Amc/0 involves: 129S2/SvPas C57BL/6 * CBA	no abnormal phenotype detected	J:192032
Ccnd1^tm2Phin/Ccnd1^tm2Phin either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6J)	no abnormal phenotype detected	J:124353
Ccnd1^tm3Pisc/Ccnd1^tm3Pisc involves: 129S4/SvJae * C57BL/6	no abnormal phenotype detected	J:156591
Ccnd1^tm3Pisc/Ccnd1^tm4Pisc involves: 129S4/SvJae * C57BL/6	no abnormal phenotype detected	J:156591
Ccnd1^tm4Pisc/Ccnd1^tm4Pisc involves: 129S4/SvJae * C57BL/6	no abnormal phenotype detected	J:156591
Ccnd1^tm5.1Pisc/Ccnd1^tm5.1Pisc Not Specified	no abnormal phenotype detected	J:192032
Tg(Fabp1-Ccnd1)2Rdb/0 C57BL/6-Tg(Fabp1-Ccnd1)2Rdb	abnormal hepatocyte morphology	J:70394
	increased liver adenoma incidence	J:70394
	increased liver weight	J:70394
	Mallory bodies	J:70394
Tg(Fabp1-Ccnd1)4Rdb/0 C57BL/6-Tg(Fabp1-Ccnd1)4Rdb/J	abnormal hepatocyte morphology	J:70394
	increased hepatocellular carcinoma incidence	J:70394
	increased hepatocyte apoptosis	J:70394
	increased liver adenoma incidence	J:70394
	increased liver weight	J:70394
	Mallory bodies	J:70394
Tg(Myh6-Ccnd1)#Ljf/0 involves: C3HeB/FeJ * DBA/2J	abnormal myocardial fiber morphology	J:40920
	abnormal myocardial fiber physiology	J:40920, J:104622
	increased heart weight	J:40920, J:104622

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