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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ccnd1
cyclin D1
MGI:88313
53 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
ApcMin/Apc+
Ccnd1tm1Dsn/Ccnd1tm1Dsn
involves: C57BL/6J
increased intestinal adenoma incidence J:78500
Ccnd1tm1Dsn/Ccnd1tm1Dsn
Ccnd2tm1Wbg/Ccnd2tm1Wbg
Ccnd3tm1Pisc/Ccnd3tm1Pisc
involves: 129P2/OlaHsd * 129S2/SvPas
abnormal common myeloid progenitor cell morphology J:92563
abnormal definitive hematopoiesis J:92563
abnormal hematopoietic stem cell morphology J:92563
abnormal interventricular septum morphology J:92563
abnormal lymphopoiesis J:92563
anemia J:92563
decreased erythrocyte cell number J:92563
decreased hematopoietic stem cell number J:92563
hydrops fetalis J:92563
lethality throughout fetal growth and development, complete penetrance J:92563
thin ventricular wall J:92563
Ccnd1tm1Dsn/Ccnd1tm1Dsn
Cdkn1btm1Mlf/Cdkn1btm1Mlf
involves: 129 * C57BL/6
abnormal corpus luteum morphology J:66707
abnormal reflex J:66707
normal craniofacial phenotype J:66707
disorganized retina layers J:66707
normal endocrine/exocrine gland phenotype J:66707
enlarged spleen J:66707
enlarged testis J:66707
enlarged thymus J:66707
female infertility J:66707
increased body weight J:66707
increased pituitary adenoma incidence J:66707
normal mortality/aging J:66707
thymus hyperplasia J:66707
Ccnd1tm1Phin/Ccnd1tm1Phin
Ccnd2tm1Wbg/Ccnd2tm1Wbg
involves: 129S2/SvPas * 129S4/SvJae * C57BL/6
abnormal cerebellum development J:105045
Ccnd1tm1Phin/Ccnd1tm1Phin
Tg(MMTV-Erbb2)NK1Mul/0
involves: 129S4/SvJae * C57BL/6 * FVB/N
decreased mammary gland tumor incidence J:105045
Ccnd1tm1Wbg/Ccnd1+
Tg(MMTVneu)202Mul/0
Tg(tetO-Ccnd1*T286A,-luc)10897Kuw/0
involves: 129S2/SvPas * FVB/N
increased mammary gland tumor incidence J:178842
Ccnd1tm1Wbg/Ccnd1+
Tg(MMTVneu)202Mul/0
Tg(tetO-Ccnd1*T286A,-luc)11233Kuw/0
involves: 129S2/SvPas * FVB/N
increased mammary gland tumor incidence J:178842
Ccnd1tm1Wbg/Ccnd1tm1Wbg
Ccnd2tm1Wbg/Ccnd2tm1Wbg
Not Specified
abnormal cerebellar granule layer morphology J:80994
absent Purkinje cell layer J:80994
ectopic Purkinje cell J:80994
impaired coordination J:80994
postnatal lethality J:80994
reduced cerebellar foliation J:80994
retina hypoplasia J:80994
small cerebellum J:80994
Ccnd1tm1Wbg/Ccnd1tm1Wbg
Ccnd3tm1Pisc/Ccnd3tm1Pisc
Not Specified
abnormal suckling behavior J:80994
aspiration J:80994
decreased body size J:80994
neonatal lethality, incomplete penetrance J:80994
retina hypoplasia J:80994
Ccnd1tm1Wbg/Ccnd1tm1Wbg
Smarcb1tm1Gvk/Smarcb1+
involves: 129/Sv * 129S2/SvPas * C57BL/6J * SJL/J
abnormal eye development J:101185
abnormal nervous system development J:101185
decreased body size J:101185
decreased tumor incidence J:101185
Ccnd1tm1Wbg/Ccnd1tm1Wbg
Tg(MMTV-tTA)25755Kuw/0
Tg(tetO-Ccnd1*T286A,-luc)10897Kuw/0
involves: 129S2/SvPas * FVB/N
normal endocrine/exocrine gland phenotype J:178842
lactation failure J:178842
Ccnd1tm1Wbg/Ccnd1tm1Wbg
Tg(MMTV-tTA)25755Kuw/0
Tg(tetO-Ccnd1*T286A,-luc)11233Kuw/0
involves: 129S2/SvPas * FVB/N
normal endocrine/exocrine gland phenotype J:178842
lactation failure J:178842
Ccnd1tm1Wbg/Ccnd1tm1Wbg
Tg(MMTVneu)202Mul/0
involves: 129S2/SvPas * FVB/N
abnormal spermatogenesis J:178842
male infertility J:178842
Ccnd1tm1Wbg/Ccnd1tm1Wbg
Tg(MMTVneu)202Mul/0
Tg(tetO-Ccnd1*T286A,-luc)10897Kuw/0
involves: 129S2/SvPas * FVB/N
increased mammary gland tumor incidence J:178842
increased tumor latency J:178842
Ccnd1tm1Wbg/Ccnd1tm1Wbg
Tg(MMTVneu)202Mul/0
Tg(tetO-Ccnd1*T286A,-luc)11233Kuw/0
involves: 129S2/SvPas * FVB/N
increased mammary gland tumor incidence J:178842
increased tumor latency J:178842
Ccnd1tm1Wbg/Ccnd1tm5.1Pisc
Tg(CAG-cre/Esr1*)5Amc/0
Tg(MMTV-Erbb2)NK1Mul/0
involves: 129S2/SvPas * C57BL/6 * CBA * FVB/N
decreased tumor growth/size J:192032
Ccnd1tm2(Ccnd2)Pisc/Ccnd1tm2(Ccnd2)Pisc
involves: 129S4/SvJae
abnormal eye electrophysiology J:95994
decreased body weight J:95994
limb grasping J:95994
normal reproductive system phenotype J:95994
Ccnd1tm4Pisc/Ccnd1tm4Pisc
Tg(MMTV-Erbb2)NK1Mul/0
involves: 129S4/SvJae * C57BL/6 * FVB/N
increased mammary adenocarcinoma incidence J:156591

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory