Ccnd2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ccnd2
cyclin D2
MGI:88314

34 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ccnd2^{tm1b(KOMP)Mbp}/Ccnd2^{tm1b(KOMP)Mbp} C57BL/6N-Ccnd2^{tm1b(KOMP)Mbp}/H	abnormal cranium morphology	J:211773
	abnormal spine curvature	J:211773
	decreased total body fat amount	J:211773
	hyperactivity	J:211773
	impaired glucose tolerance	J:211773
	increased bone mineral content	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating glucose level	J:211773
	increased circulating iron level	J:211773
	increased circulating phosphate level	J:211773
	increased fasting circulating glucose level	J:211773
	increased grip strength	J:211773
	increased lean body mass	J:211773
	increased mean corpuscular volume	J:211773
	small testis	J:211773
	trunk curl	J:211773
Ccnd2^tm1Wbg/Ccnd2^tm1Wbg involves: 129S2/SvPas	abnormal ovarian folliculogenesis	J:37092
	abnormal ovulation	J:37092
	decreased testis weight	J:37092
	female infertility	J:37092
	oligozoospermia	J:37092
Ccnd2^tm1Wbg/Ccnd2^tm1Wbg involves: 129S2/SvPas * C57BL/6J	abnormal cerebellar foliation	J:52358
	abnormal cerebellar granule layer morphology	J:52358
	abnormal cerebellar molecular layer	J:52358
	abnormal cerebellum external granule cell layer morphology	J:52358
	abnormal cerebellum morphology	J:52358
	abnormal Purkinje cell dendrite morphology	J:52358
	abnormal Purkinje cell morphology	J:52358
	small cerebellum	J:52358
	thin external granule cell layer	J:52358
Tg(Myh6-Ccnd2)1Ljf/0 involves: C3HeB/FeJ * DBA/2J	abnormal myocardial fiber physiology	J:104622
	abnormal response to cardiac infarction	J:104622
	decreased myocardial infarct size	J:104622
	increased heart weight	J:104622

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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