Ccnd3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ccnd3
cyclin D3
MGI:88315

17 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ccnd3^{tm1.1(Ccnd2)Iaai}/Ccnd3^{tm1.1(Ccnd2)Iaai} involves: 129S6/SvEvTac	abnormal bone marrow cell physiology	J:192031
	decreased B cell proliferation	J:192031
	decreased bone marrow cell number	J:192031
	decreased double-positive T cell number	J:192031
	decreased pre-B cell number	J:192031
	decreased T cell proliferation	J:192031
	small thymus	J:192031
	thymus hypoplasia	J:192031
Ccnd3^tm1Pisc/Ccnd3^tm1Pisc Not Specified	decreased B cell proliferation	J:192031
	decreased bone marrow cell number	J:192031
	decreased double-positive T cell number	J:88120, J:192031
	decreased lymphocyte cell number	J:88120
	decreased pre-B cell number	J:192031
	decreased T cell proliferation	J:88120, J:192031
	increased double-negative T cell number	J:88120
	small thymus	J:192031
	thymus hypoplasia	J:88120, J:192031
Ccnd3^tm2.1Pisc/Ccnd3^tm2.1Pisc Tg(CAG-cre/Esr1)5Amc/0 involves: C57BL/6 CBA	no abnormal phenotype detected	J:192032
Ccnd3^tm2.1Pisc/Ccnd3^tm2.1Pisc Tg(Mx1-cre)1Cgn/0 involves: C57BL/6 * CBA	abnormal hematopoietic stem cell physiology	J:192032
	abnormal hematopoietic system morphology/development	J:192032
	decreased double-positive T cell number	J:192032
	decreased erythrocyte cell number	J:192032
	decreased leukocyte cell number	J:192032
	small thymus	J:192032
Tg(Myh6-Ccnd3)1Ljf/0 involves: C3HeB/FeJ * DBA/2J	abnormal myocardial fiber physiology	J:104622
Tg(Myh6-Ccnd3)1Ljf/0 involves: C3HeB/FeJ * DBA/2J	increased heart weight	J:104622

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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