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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ccnd3
cyclin D3
MGI:88315
31 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ccnd1tm1Dsn/Ccnd1tm1Dsn
Ccnd2tm1Wbg/Ccnd2tm1Wbg
Ccnd3tm1Pisc/Ccnd3tm1Pisc
involves: 129P2/OlaHsd * 129S2/SvPas 		abnormal common myeloid progenitor cell morphology J:92563
abnormal definitive hematopoiesis J:92563
abnormal hematopoietic stem cell morphology J:92563
abnormal interventricular septum morphology J:92563
abnormal lymphopoiesis J:92563
anemia J:92563
decreased erythrocyte cell number J:92563
decreased hematopoietic stem cell number J:92563
hydrops fetalis J:92563
lethality throughout fetal growth and development, complete penetrance J:92563
thin ventricular wall J:92563
Ccnd1tm1Wbg/Ccnd1tm1Wbg
Ccnd3tm1Pisc/Ccnd3tm1Pisc
Not Specified 		abnormal suckling behavior J:80994
aspiration J:80994
decreased body size J:80994
neonatal lethality, incomplete penetrance J:80994
retina hypoplasia J:80994
Ccnd2tm1Wbg/Ccnd2tm1Wbg
Ccnd3tm1Pisc/Ccnd3tm1Pisc
Not Specified 		abnormal erythropoiesis J:80994
abnormal liver development J:80994
lethality throughout fetal growth and development, complete penetrance J:80994
low mean erythrocyte cell number J:80994
macrocytic anemia J:80994
macrocytosis J:80994
Ccnd3tm1Pisc/Ccnd3tm1Pisc
Cdkn1btm1Mlf/Cdkn1btm1Mlf
involves: 129S4/SvJaeSor 		abnormal bone marrow cell physiology J:192031
decreased double-positive T cell number J:192031
decreased T cell proliferation J:192031
thymus hypoplasia J:192031
Ccnd3tm1Pisc/Ccnd3tm1Pisc
Cdkn1btm1Mlf/Cdkn1btm1Mlf
Rb1tm2Brn/Rb1tm2Brn
Tg(Mx1-cre)1Cgn/0
involves: 129S4/SvJaeSor * C57BL/6 * CBA 		normal immune system phenotype J:192031
Ccnd3tm1Pisc/Ccnd3tm1Pisc
Rag2tm1Fwa/Rag2tm1Fwa
involves: 129S/SvEv 		increased T cell proliferation J:88120
Ccnd3tm1Pisc/Ccnd3tm1Pisc
Rb1tm2Brn/Rb1tm2Brn
Tg(Mx1-cre)1Cgn/0
involves: 129 * C57BL/6 * CBA 		decreased double-positive T cell number J:192031
decreased T cell proliferation J:192031
thymus hypoplasia J:192031
Ccnd3tm1Pisc/Ccnd3tm1Pisc
Tg(Lck)4220Rmp/0
involves: C57BL/6J * DBA/2 		decreased lymphoma incidence J:88120
decreased tumor-free survival time J:88120
increased T cell derived lymphoma incidence J:88120
Ccnd3tm1Pisc/Ccnd3tm1Pisc
Trp53tm1Tyj/Trp53tm1Tyj
involves: 129S2/SvPas 		increased T cell derived lymphoma incidence J:88120
premature death J:88120
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory