Cd14 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cd14
CD14 antigen
MGI:88318

22 phenotypes from 3 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cd14^hdl/Cd14^hdl C57BL/6-Cd14^hdl	abnormal interferon secretion	J:98908
	decreased susceptibility to endotoxin shock	J:98908
	decreased tumor necrosis factor secretion	J:98908
	increased susceptibility to Riboviria infection	J:98908
Cd14^tm1Frm/Cd14⁺ involves: 129S4/SvJae * C57BL/6J	abnormal cytokine secretion	J:65107
	decreased interleukin-6 secretion	J:65107
	decreased tumor necrosis factor secretion	J:65107
Cd14^tm1Frm/Cd14^tm1Frm B6.129S4-Cd14^tm1Frm	abnormal cytokine level	J:96680
	abnormal interleukin level	J:96680
	abnormal tumor necrosis factor level	J:96680
	decreased susceptibility to bone fracture	J:118467
	decreased total body fat amount	J:118467
	increased bone mass	J:118467
	increased bone mineral content	J:118467
	increased bone mineral density	J:118467
	increased lean body mass	J:118467
	pulmonary edema	J:96680
Cd14^tm1Frm/Cd14^tm1Frm involves: 129S4/SvJae	abnormal interferon secretion	J:98908
	decreased susceptibility to endotoxin shock	J:98908
	increased susceptibility to Riboviria infection	J:98908
Cd14^tm1Frm/Cd14^tm1Frm involves: 129S4/SvJae * C57BL/6J	abnormal cytokine secretion	J:65107
	decreased interleukin-6 secretion	J:65107
	decreased tumor necrosis factor secretion	J:65107
Cd14^tm1Smg/Cd14^tm1Smg B6.129S1-CD14^tm1Smg	decreased susceptibility to bacterial infection	J:127072
Cd14^tm1Smg/Cd14^tm1Smg C.129S1-CD14^tm1Smg	abnormal macrophage physiology	J:116691
	abnormal neutrophil physiology	J:127072
	decreased susceptibility to bacterial infection	J:127072
	decreased tumor necrosis factor secretion	J:116691
Cd14^tm1Smg/Cd14^tm1Smg involves: 129S1/Sv	abnormal tumor necrosis factor level	J:103464
Cd14^tm1Smg/Cd14^tm1Smg involves: 129S1/Sv * C57BL/6	decreased circulating interleukin-6 level	J:32729
	decreased circulating tumor necrosis factor level	J:32729
	decreased interleukin-6 secretion	J:32729
	decreased susceptibility to bacterial infection	J:32729
	decreased susceptibility to bacterial infection induced morbidity/mortality	J:32729
	decreased susceptibility to endotoxin shock	J:32729
	decreased tumor necrosis factor secretion	J:32729

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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