Cd27 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cd27
CD27 antigen
MGI:88326

19 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cd27^{em1(IMPC)Ccpcz}/Cd27^{em1(IMPC)Ccpcz} C57BL/6NCrl-Cd27^{em1(IMPC)Ccpcz}/Ccpcz	abnormal digit morphology	J:211773
	abnormal heart morphology	J:211773
	abnormal seminal vesicle morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal testis morphology	J:211773
	decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number	J:211773
	decreased lean body mass	J:211773
	enlarged heart	J:211773
	increased prepulse inhibition	J:211773
	small seminal vesicle	J:211773
	small testis	J:211773
Cd27^tm1Jbo/Cd27^tm1Jbo B6.129P2-Cd27^tm1Jbo	abnormal leukopoiesis	J:97606
	decreased regulatory T cell number	J:198200
	normal immune system phenotype	J:198200
	increased leukocyte cell number	J:97606
	increased T cell apoptosis	J:198200
Cd27^tm1Jbo/Cd27^tm1Jbo either: B6.129P2-CD27^tm1Jbo or 129P2/OlaHsd-Tnfrsf7^tm1Jbo	abnormal CD4-positive, alpha-beta T cell physiology	J:65516
	abnormal cytotoxic T cell physiology	J:65516
	abnormal T cell physiology	J:65516

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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