Cd3e Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cd3e
CD3 antigen, epsilon polypeptide
MGI:88332

26 phenotypes from 7 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cd3e^m1Btlr/Cd3e^m1Btlr C57BL/6J-Cd3e^m1Btlr	abnormal thymus morphology	J:132486
	absent T cells	J:132486
	arrested T cell differentiation	J:132486
	increased T cell apoptosis	J:132486
	seizures	J:132486
	small thymus	J:132486
Cd3e^m1Btlr/Cd3e^m1Btlr involves: C57BL/6J	abnormal class switch recombination	J:185495
Cd3e^m2Btlr/Cd3e^m2Btlr C57BL/6J-Cd3e^m2Btlr	abnormal CD8-positive, alpha-beta T cell differentiation	J:274934
	abnormal T cell differentiation	J:274934
	decreased CD4-positive, alpha-beta T cell number	J:274934
	decreased CD8-positive, naive alpha-beta T cell number	J:274934
	increased CD8-positive, alpha-beta T cell number	J:274934
	increased central memory CD8 positive, alpha-beta T cell number	J:274934
Cd3e^tm1.1Geno/Cd3e^tm1.1Geno involves: C57BL/6	abnormal double-positive T cell morphology	J:192604
	abnormal T cell differentiation	J:192604
	abnormal T cell number	J:192604
	increased DN3 thymocyte number	J:192604
Cd3e^tm1.1Lov/Cd3e^tm1.1Lov Not Specified	abnormal T cell morphology	J:72144
	arrested T cell differentiation	J:72144
	decreased double-positive T cell number	J:72144
	increased double-negative T cell number	J:72144
Cd3e^tm1Cpt/Cd3e^tm1Cpt involves: 129S4/SvJae * C57BL/6	absent T cells	J:54756
	decreased double-positive T cell number	J:54756
	thymus hypoplasia	J:54756
Cd3e^tm1Lov/Cd3e^tm1Lov involves: 129S1/Sv * 129X1/SvJ	abnormal T cell morphology	J:72144
	arrested T cell differentiation	J:72144
	decreased double-positive T cell number	J:72144
	increased double-negative T cell number	J:72144
Cd3e^tm1Mal/Cd3e^tm1Mal C57BL/6-Cd3e^tm1Mal	abnormal B cell morphology	J:81133
	abnormal double-negative T cell morphology	J:81133
	abnormal regulatory T cell physiology	J:125748
	absent T cells	J:131351
	arrested T cell differentiation	J:81133
	increased susceptibility to induced morbidity/mortality	J:125748
Cd3e^tm1Mal/Cd3e^tm1Mal involves: C57BL/6	absent CD4-positive, alpha-beta T cells	J:77098
	absent CD8-positive, alpha-beta T cells	J:77098
	arrested T cell differentiation	J:77098

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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