Cd5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cd5
CD5 antigen
MGI:88340

18 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cd5^{tm1.1(KOMP)Mbp}/Cd5^{tm1.1(KOMP)Mbp} C57BL/6N-Cd5^{tm1.1(KOMP)Mbp}/Ucd	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal uterus morphology	J:211773
	enlarged spleen	J:211773
	increased spleen weight	J:211773
Cd5^tm1.1Chra/Cd5^tm1.1Chra involves: C57BL/6 * FVB/N	abnormal T cell anergy	J:189919
	abnormal T cell physiology	J:189919
	decreased B cell number	J:189919
	decreased CD4-positive, alpha-beta T cell number	J:189919
	decreased double-positive T cell number	J:189919
	decreased follicular B cell number	J:189919
	decreased susceptibility to experimental autoimmune encephalomyelitis	J:189919
	decreased T cell proliferation	J:189919
	decreased T-helper 17 cell number	J:189919
	increased double-negative T cell number	J:189919
	increased T cell proliferation	J:189919
Cd5^tm1Cgn/Cd5^tm1Cgn B6.129P2-Cd5^tm1Cgn	abnormal T cell anergy	J:189919
	decreased susceptibility to experimental autoimmune encephalomyelitis	J:189919
	increased regulatory T cell number	J:189919
	increased T cell proliferation	J:189919
Cd5^tm1Cgn/Cd5^tm1Cgn involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:19317

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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