Cd68 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cd68
CD68 antigen
MGI:88342

11 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cd68^em1(IMPC)Bay/Cd68⁺ C57BL/6N-Cd68^em1(IMPC)Bay/BayMmucd	abnormal locomotor behavior	J:211773
Cd68^em1(IMPC)Bay/Cd68^em1(IMPC)Bay C57BL/6N-Cd68^em1(IMPC)Bay/BayMmucd	preweaning lethality, incomplete penetrance	J:211773
Cd68^tm1Shnd/Cd68^tm1Shnd either: B6.129-Cd68^tm1Shnd or (involves: 129S1/Sv * 129X1/SvJ)	abnormal dendritic cell antigen presentation	J:175275
Cd68^tm1Xfen/Cd68⁺ C57BL/6J-Cd68^tm1Xfen	increased bone mineralization	J:178120
Cd68^tm1Xfen/Cd68^tm1Xfen C57BL/6J-Cd68^tm1Xfen	abnormal osteoclast morphology	J:178120
	abnormal osteoclast physiology	J:178120
	abnormal trabecular bone morphology	J:178120
	decreased bone mineral density	J:178120
	decreased bone resorption	J:178120
	increased bone mineralization	J:178120
	increased bone trabecula number	J:178120
	increased bone volume	J:178120

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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