Cd8b1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cd8b1
CD8 subunit beta 1
MGI:88347

8 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cd8a^tm1Asin/Cd8a^tm1Asin Cd8b1^tm1Litt/Cd8b1^tm1Litt H2-Ab1^b-tm1Gru/H2-Ab1^b-tm1Gru involves: 129 * FVB/N	decreased CD4-positive, alpha-beta T cell number	J:126026
	increased CD8-positive, alpha-beta T cell number	J:126026
Cd8b1^tm1Litt/Cd8b1⁺ Tg(TcraH-Y,TcrbH-Y)71Vbo/0 involves: 129S4/SvJae * C57BL/6J * DBA/2	decreased double-positive T cell number	J:112551
Cd8b1^tm1Litt/Cd8b1^tm1Litt Tg(TcraH-Y,TcrbH-Y)71Vbo/0 involves: 129S4/SvJae * C57BL/6J * DBA/2	abnormal lymph node cell ratio	J:112551
	abnormal negative T cell selection	J:112551
	abnormal positive T cell selection	J:112551
	decreased CD8-positive, alpha-beta T cell number	J:112551
	increased CD4-positive, alpha-beta T cell number	J:112551

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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