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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Cdk1
cyclin dependent kinase 1
MGI:88351
20 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cdk1tm1(Cdk2)Kald/Cdk1+
involves: 129 * C57BL/6 		no abnormal phenotype detected J:141249
Cdk1tm1(Cdk2)Kald/Cdk1+
Cdk2tm1Kald/Cdk2tm1Kald
involves: 129S1/Sv * C57BL/6 		abnormal female reproductive system morphology J:141249
abnormal male meiosis J:141249
abnormal male reproductive system morphology J:141249
abnormal spermatid morphology J:141249
abnormal spermatocyte morphology J:141249
abnormal spermatogenesis J:141249
absent oocytes J:141249
absent ovarian follicles J:141249
female infertility J:141249
increased male germ cell apoptosis J:141249
infertility J:141249
male infertility J:141249
small ovary J:141249
small seminiferous tubules J:141249
small testis J:141249
Cdk1tm1(Cdk2)Kald/Cdk1tm1(Cdk2)Kald
involves: 129 * C57BL/6 		embryonic lethality before implantation, complete penetrance J:141249
Cdk1tm3Kald/Cdk1+
Fbxo43tm1.2Kald/Fbxo43tm1.2Kald
Gt(ROSA)26Sortm1(cre/ERT)Brn/Gt(ROSA)26Sor+
involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL 		arrest of male meiosis J:251984
azoospermia J:251984
increased male germ cell apoptosis J:251984
premature death J:251984
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory