Cdh1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cdh1
cadherin 1
MGI:88354

43 phenotypes from 13 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cdh1^tm1.1Mpst/Cdh1^tm1.1Mpst B6.129P2-Cdh1^tm1.1Mpst	abnormal placenta morphology	J:163273
	abnormal placenta physiology	J:163273
	abnormal placental labyrinth vasculature morphology	J:163273
	abnormal trophoblast layer morphology	J:163273
	decreased placental labyrinth size	J:163273
	embryonic growth arrest	J:163273
	embryonic lethality during organogenesis, complete penetrance	J:163273
	pale yolk sac	J:163273
	pallor	J:163273
	placental labyrinth hypoplasia	J:163273
Cdh1^{tm1a(EUCOMM)Wtsi}/Cdh1^{tm1a(EUCOMM)Wtsi} B6Brd;B6Dnk;B6N-Tyr^c-Brd Cdh1^{tm1a(EUCOMM)Wtsi}/Wtsi	preweaning lethality, complete penetrance	J:211773
Cdh1^tm1Cbm/Cdh1^tm1Cbm involves: 129P2/OlaHsd	abnormal preimplantation embryo development	J:22631
	absent blastocoele	J:22631
	embryonic lethality, complete penetrance	J:22631
	failure of blastocyst to hatch from the zona pellucida	J:22631
	failure of morula compaction	J:22631
Cdh1^tm1Jjon/Cdh1^tm1Jjon Tg(KRT14-cre)8Brn/0 involves: 129P2/OlaHsd * FVB/N	no abnormal phenotype detected	J:116152
Cdh1^tm1Jjon/Cdh1^tm1Jjon Tg(Wap-cre)51Nki/0 involves: 129P2/OlaHsd * FVB/N	hypolactation	J:171765
	normal neoplasm	J:171765
Cdh1^tm1Kem/Cdh1^tm1Kem involves: 129S2/SvPas	absent blastocoele	J:183847
Cdh1^tm1Kem/Cdh1^tm1Kem involves: 129S2/SvPas * C57BL/6	abnormal embryonic tissue morphology	J:19904
	abnormal extraembryonic tissue morphology	J:19904
	absent blastocoele	J:19904
	absent trophectoderm	J:19904
	embryonic lethality before implantation, complete penetrance	J:19904
Cdh1^tm1Kem/Cdh1^tm2.1Kem involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6	abnormal cell adhesion	J:77170
Cdh1^tm1Kem/Cdh1^tm2Kem Tg(MMTV-cre)1Kem/0 involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6	abnormal mammary gland growth during lactation	J:77170
	abnormal mammary gland growth during pregnancy	J:77170
	abnormal milk composition	J:77170
	lactation failure	J:77170
Cdh1^tm1Mlec/Cdh1^tm1Mlec involves: 129S2/SvPas	abnormal enterocyte physiology	J:142843
Cdh1^tm1Mlec/Cdh1^tm1Mlec involves: 129S2/SvPas	increased susceptibility to bacterial infection	J:142843
Cdh1^tm2Kem/Cdh1^tm2Kem Tg(Ins2-cre)23Herr/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA/J	abnormal blood vessel morphology	J:196410
	abnormal pancreatic islet morphology	J:196410
	decreased insulin secretion	J:196410
	normal growth/size/body region phenotype	J:196410
	impaired glucose tolerance	J:196410
	increased pancreatic beta cell mass	J:196410
	increased pancreatic beta cell proliferation	J:196410
Cdh1^tm2Kem/Cdh1^tm5(Cdh2)Kem involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal trophectoderm morphology	J:117056
	embryonic lethality between implantation and somite formation, complete penetrance	J:117056
Cdh1^tm3.1Kem/Cdh1^tm3.1Kem involves: 129P2/OlaHsd * C57BL/6	prenatal lethality	J:96963
Cdh1^tm3.2Kem/Cdh1^tm3.2Kem involves: 129P2/OlaHsd * C57BL/6	prenatal lethality, complete penetrance	J:96963
Cdh1^tm3Kem/Cdh1^tm3Kem involves: 129P2/OlaHsd * C57BL/6	prenatal lethality, complete penetrance	J:96963
Cdh1^tm4(Cdh2)Kem/Cdh1^tm4(Cdh2)Kem involves: 129P2/OlaHsd * C57BL/6	abnormal embryo development	J:117056
	embryonic lethality between implantation and somite formation, complete penetrance	J:117056
	empty decidua capsularis	J:117056
Cdh1^tm5(Cdh2)Kem/Cdh1^tm5(Cdh2)Kem involves: 129P2/OlaHsd * C57BL/6	abnormal embryonic tissue morphology	J:117056
	absent blastocoele	J:117056
	absent trophectoderm	J:117056
	embryonic lethality between implantation and somite formation, complete penetrance	J:117056
	empty decidua capsularis	J:117056
	failure of blastocyst to hatch from the zona pellucida	J:117056

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