F3 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

F3
coagulation factor III
MGI:88381

18 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
F2r^tm1Pago/F2r^tm1Pago F3^tm1.1Dwr/F3^tm1.1Dwr B6.129-F3^tm1.1Dwr F2r^tm1Pago	abnormal induced retina neovascularization	J:135087
F2rl1^tm1Bpd/F2rl1^tm1Bpd F3^tm1.1Dwr/F3^tm1.1Dwr B6.129-F3^tm1.1Dwr F2rl1^tm1Bpd	normal cardiovascular system phenotype	J:135087
F3^tm1(F3)Lasn/F3^tm1(F3)Lasn involves: 129S/SvEvBrd * C57BL/6	normal homeostasis/metabolism phenotype	J:131547, J:133293
	increased lung adenoma incidence	J:133293
	increased lung carcinoma incidence	J:133293
F3^tm1Dco/F3^tm1Dco Procr^tm1Cte/Procr^tm1Cte involves: 129S7/SvEvBrd * BALB/c * Black Swiss * C57BL/6 * FVB/N	prenatal lethality, complete penetrance	J:119529
F3^tm1Dco/F3^tm1Dco Procr^tm1Cte/Procr^tm1Cte Tg(F3)1Nmk/0 involves: 129S7/SvEvBrd * BALB/c * Black Swiss * C57BL/6 * FVB/N	normal mortality/aging	J:119529
F3^tm1Dco/F3^tm1Dco Tg(F3)1Nmk/0 B6.Cg-F3^tm1Dco Tg(F3)1Nmk	abnormal blood coagulation	J:88245
	abnormal interleukin level	J:88245
	decreased susceptibility to endotoxin shock	J:88245
	decreased susceptibility to induced morbidity/mortality	J:88245
F3^tm1Dco/F3^tm1Dco Tg(F3)1Nmk/0 involves: 129/Sv * BALB/c * C57BL/6	no abnormal phenotype detected	J:82528
F3^tm1Dco/F3^tm1Dco Tg(F3)1Nmk/? involves: BALB/c * C57BL/6	cardiac fibrosis	J:137921
F3^tm1Dco/F3^tm1Dco Thbd^tm2Rdr/Thbd^tm2Rdr involves: 129S2/SvPas * C57BL/6	abnormal pericardial cavity morphology	J:82224
	abnormal vitelline vasculature morphology	J:82224
	absent vitelline blood vessels	J:82224
	embryonic lethality during organogenesis, complete penetrance	J:82224
F3^tm1Dco/F3^tm1Dco Thbd^tm2Rdr/Thbd^tm2Rdr Tg(F3)1Nmk/0 involves: 129/Sv * 129S2/SvPas * BALB/c * C57BL/6	normal mortality/aging	J:82224
	placenta hemorrhage	J:82224
F3^tm1Nmk/F3^tm1Nmk Myl2^tm1(cre)Krc/? Tg(Myh6-F3)4Nmk/? involves: 129S4/SvJae * 129S6/SvEvTac * BALB/c * C57BL/6	normal cardiovascular system phenotype	J:137921

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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