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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Chrm2
cholinergic receptor, muscarinic 2, cardiac
MGI:88397
16 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Chrm2tm1Jwe/Chrm2+
involves: 129S4/SvJae * CF-1 		decreased physiological sensitivity to xenobiotic J:53061
impaired behavioral response to xenobiotic J:53061
Chrm2tm1Jwe/Chrm2tm1Jwe
B6.129S4-Chrm2tm1Jwe 		abnormal sexual interaction J:134260
abnormal vocalization J:134260
decreased mounting behavior J:134260
Chrm2tm1Jwe/Chrm2tm1Jwe
involves: 129S4/SvJae * CF-1 		abnormal CNS synaptic transmission J:112505
abnormal gallbladder physiology J:125455
abnormal heart rate J:60451
normal cardiovascular system phenotype J:102321
decreased body weight J:53061
decreased bronchoconstrictive response J:104034
decreased chemically-elicited antinociception J:53061
decreased physiological sensitivity to xenobiotic J:53061
impaired behavioral response to xenobiotic J:60451
impaired smooth muscle contractility J:60451, J:125455
Chrm2tm1Minm/Chrm2tm1Minm
involves: 129X1/SvJ * C57BL/6 		normal muscle phenotype J:99247
normal renal/urinary system phenotype J:99247
normal vision/eye phenotype J:99247
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
MGI 6.24 		The Jackson Laboratory