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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Chrm4
cholinergic receptor, muscarinic 4
MGI:88399
20 phenotypes from 4 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Chrm4tm1b(EUCOMM)Hmgu/Chrm4tm1b(EUCOMM)Hmgu
B6N(Cg)-Chrm4tm1b(EUCOMM)Hmgu/J
hyperactivity J:211773
increased startle reflex J:211773
Chrm4tm1Jwe/Chrm4tm1Jwe
B6.129S6-Chrm4tm1Jwe
abnormal vocalization J:134260
Chrm4tm1Jwe/Chrm4tm1Jwe
involves: 129S6/SvEvTac * CF-1
abnormal CNS synaptic transmission J:112505
abnormal gallbladder physiology J:125455
abnormal heart rate J:60451
decreased body weight J:57480
normal homeostasis/metabolism phenotype J:57480
impaired smooth muscle contractility J:125455
increased locomotor activity J:57480
normal muscle phenotype J:60451
Chrm4tm1Minm/Chrm4tm1Minm
involves: 129X1/SvJ * DBA/2J
abnormal behavioral response to xenobiotic J:99248
abnormal locomotor behavior J:99248
Chrm4tm2.1Jwe/Chrm4tm2.1Jwe
Tg(Drd1a-cre)AGsc/0
involves: 129S6/SvEvTac * C57BL/6 * FVB/N
abnormal neuron physiology J:157841
catalepsy J:157841
enhanced behavioral response to addictive substance J:157841
enhanced behavioral response to cocaine J:157841
enhanced behavioral response to xenobiotic J:157841
hyperactivity J:157841
impaired behavioral response to xenobiotic J:157841
increased dopamine level J:157841

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory