Vsx2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Vsx2
visual system homeobox 2
MGI:88401

32 phenotypes from 5 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Vsx2^or-2J/Vsx2^or-2J NOR2/LtDn-Vsx2^or-2J/J	abnormal eye development	J:30714
	abnormal gametogenesis	J:30714
	abnormal lens development	J:30714
	female infertility	J:30714
	male infertility	J:30714
	microphthalmia	J:30714
Vsx2^or-J/Vsx2^or-2J involves: 129S1/Sv * NOR2/LtDn	normal reproductive system phenotype	J:30714
Vsx2^or-J/Vsx2^or-J 129S1/Sv	abnormal cell death	J:5966
	abnormal eye development	J:5767
	abnormal hyaloid artery morphology	J:5767
	abnormal lens development	J:5767
	abnormal optic cup morphology	J:5767
	abnormal optic fissure morphology	J:5767
	abnormal optic stalk morphology	J:5767, J:5966
	abnormal retina ganglion cell morphology	J:5966
	abnormal retina progenitor cell morphology	J:5767
	absent optic nerve	J:5767
	decreased eye pigmentation	J:5767
	disorganized retina layers	J:5767
	eyelids fail to open	J:5767
	microphthalmia	J:5767
	small lens	J:5767
Vsx2^or-J/Vsx2^or-J involves: 129S1/Sv	abnormal retina development	J:190452
	abnormal retina morphology	J:190452
	abnormal retina pigment epithelium morphology	J:190452
	abnormal retina pigmentation	J:190452
	decreased total retina thickness	J:190452
	microphthalmia	J:190452
	small lens	J:190452
Vsx2^or-J/Vsx2^tm1.1Eml involves: 129S1/Sv * 129X1/SvJ	microphthalmia	J:190452
Vsx2^or/Vsx2^or involves: C57BL/Gr	abnormal cell cycle checkpoint function	J:5575
	abnormal eye development	J:307
	abnormal lens morphology	J:307
	abnormal optic nerve morphology	J:307
	abnormal optic stalk morphology	J:307
	absent optic chiasm	J:307
	absent optic nerve	J:307
	Harderian gland hypertrophy	J:307
	lacrimal gland hypertrophy	J:307
	microphthalmia	J:307
Vsx2^tm1.1Eml/Vsx2^tm1.1Eml involves: 129S1/Sv * 129X1/SvJ	abnormal eye morphology	J:190452
	abnormal retina development	J:190452
	abnormal retina pigment epithelium morphology	J:190452
	abnormal retina pigmentation	J:190452
	abnormal vitreous body morphology	J:190452
	decreased total retina thickness	J:190452
	microphthalmia	J:190452
	small lens	J:190452
Vsx2^tm1.1Itl/Vsx2^tm1.1Itl involves: 129S6/SvEvTac	abnormal retina development	J:190452
	abnormal retina pigment epithelium morphology	J:190452
	abnormal retina pigmentation	J:190452
	decreased total retina thickness	J:190452
	microphthalmia	J:190452
	small lens	J:190452

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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