Cnp Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
MGI:88437

77 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Abcd1^tm1Kan/Y Gt(ROSA)26Sor^{tm2.1(CAG-ELOVL1)Geno}/Gt(ROSA)26Sor⁺ Cnp^tm1(cre)Kan/Cnp⁺ involves: 129 * 129S1/Sv * 129X1/SvJ * C57BL/6J	increased fatty acids level	J:257393
Anln^{tm1c(EUCOMM)Wtsi}/Anln^{tm1c(EUCOMM)Wtsi} Cnp^tm1(cre)Kan/Cnp⁺ involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6N	abnormal myelination	J:272250
	decreased nerve conduction velocity	J:272250
	normal nervous system phenotype	J:272250
	tomacula	J:272250
Cmtm5^{tm1c(KOMP)Wtsi}/Cmtm5^{tm1c(KOMP)Wtsi} Cnp^tm1(cre)Kan/Cnp⁺ B6.Cg-Cnp^tm1(cre)Kan Cmtm5^{tm1c(KOMP)Wtsi}	abnormal axon morphology	J:327261
	abnormal visual evoked potential	J:327261
	astrocytosis	J:327261
	axon degeneration	J:327261
	normal behavior/neurological phenotype	J:327261
	microgliosis	J:327261
Cnp^tm1(cre)Kan/Cnp⁺ Tfam^tm1Lrsn/Tfam^tm1Lrsn involves: 129S1/Sv * 129X1/SvJ	abnormal colon morphology	J:228933
	abnormal enteric neuron morphology	J:228933
	abnormal PNS glial cell morphology	J:228933
	abnormal small intestine morphology	J:228933
	axon degeneration	J:228933
	decreased body size	J:228933
	decreased mitochondrial DNA content	J:228933
	decreased neuron mitochondrial DNA content	J:228933
	decreased neuron number	J:228933
	distended abdomen	J:228933
	neurodegeneration	J:228933
	postnatal growth retardation	J:228933
	premature death	J:228933
Cnp^tm1(cre)Kan/Cnp⁺ Pten^tm1Hwu/Pten^tm1Hwu B6N.129-Cnp^tm1(cre)Kan Pten^tm1Hwu	tomacula	J:236408
Cnp^tm1(cre)Kan/Cnp⁺ Septin8^{tm1c(EUCOMM)Wtsi}/Septin8^{tm1c(EUCOMM)Wtsi} B6N.Cg-Septin8^{tm1c(EUCOMM)Wtsi} Cnp^tm1(cre)Kan	decreased nerve conduction velocity	J:236408
	normal nervous system phenotype	J:236408
	tomacula	J:236408
Drp2^tm1.1Brp/Y Cnp^tm1(cre)Kan/Cnp⁺ involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal myelin sheath morphology	J:185953
	abnormal Schwann cell morphology	J:185953
	hypermyelination	J:185953
	increased Schwann cell number	J:185953
	normal nervous system phenotype	J:185953
Erbb3^tm2Cbm/Erbb3^tm3Cbm Erbb4^tm1Fej/Erbb4^tm1Fej Cnp^tm1(cre)Kan/? involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ	abnormal myelination	J:145464
	normal nervous system phenotype	J:145464
	postnatal lethality, complete penetrance	J:145464
Fa2h^tm1Hama/Fa2h^tm1Hama Cnp^tm1(cre)Kan/Cnp⁺ involves: 129 * C57BL/6	abnormal cerebellum morphology	J:171655
	abnormal galactolipid level	J:171655
	abnormal lipid level	J:171655
	abnormal Purkinje cell morphology	J:171655
	normal behavior/neurological phenotype	J:171655
	decreased locomotor activity	J:171655
	decreased Purkinje cell size	J:171655
	decreased vertical activity	J:171655
	impaired coordination	J:171655
Fdft1^tm1Kan/Fdft1^tm1Kan Cnp^tm1(cre)Kan/Cnp⁺ involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ	ataxia	J:98525
	demyelination	J:98525
	impaired coordination	J:98525
	impaired limb coordination	J:98525
	normal nervous system phenotype	J:98525
	postnatal growth retardation	J:98525
	premature death	J:98525
	reduced fertility	J:98525
	tremors	J:98525
Gt(ROSA)26Sor^tm1(DTA)Riet/Gt(ROSA)26Sor⁺ Cnp^tm1(cre)Kan/Cnp⁺ involves: 129P2/OlaHsd	absent oligodendrocytes	J:92789
	axon degeneration	J:92789
	demyelination	J:92789
	paraparesis	J:92789
	postnatal lethality, complete penetrance	J:92789
	tremors	J:92789
	weight loss	J:92789
Gt(ROSA)26Sor^tm2(DTA)Riet/Gt(ROSA)26Sor⁺ Cnp^tm1(cre)Kan/Cnp⁺ involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ	absent oligodendrocytes	J:110983
	axon degeneration	J:110983
	demyelination	J:110983
	paraparesis	J:110983
	postnatal lethality, complete penetrance	J:110983
	tremors	J:110983
	weight loss	J:110983
Hsd17b4^tm2Baes/Hsd17b4^tm2Baes Cnp^tm1(cre)Kan/Cnp⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	normal behavior/neurological phenotype	J:201698
	normal growth/size/body region phenotype	J:201698
	increased fatty acids level	J:201698
	normal nervous system phenotype	J:201698
	normal reproductive system phenotype	J:201698
Mtor^tm1Koz/Mtor^tm1Koz Cnp^tm1(cre)Kan/Cnp⁺ involves: 129S4/SvJae * C57BL/6	abnormal axolemma morphology	J:181341
	abnormal axon morphology	J:181341
	abnormal internode morphology	J:181341
	abnormal motor coordination/balance	J:181341
	abnormal myelin sheath morphology	J:181341
	abnormal myelination	J:181341
	abnormal Schwann cell morphology	J:181341
	decreased nerve conduction velocity	J:181341
	decreased Schwann cell number	J:181341
Myrf^tm1Barr/Myrf^tm1Barr Cnp^tm1(cre)Kan/Cnp⁺ involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6	abnormal myelination	J:150563
	abnormal oligodendrocyte morphology	J:150563
	abnormal spinal cord morphology	J:150563
	postnatal lethality, complete penetrance	J:150563
	seizures	J:150563
	tremors	J:150563
Nfasc^tm1Bhat/Nfasc^tm1Bhat Cnp^tm1(cre)Kan/? involves: 129S1/Sv * 129X1/SvJ	abnormal axon morphology	J:145846
	abnormal limb posture	J:145846
	abnormal motor capabilities/coordination/movement	J:145846
	abnormal motor coordination/balance	J:145846
	abnormal Purkinje cell axon morphology	J:145846
	decreased locomotor activity	J:145846
	decreased nerve conduction velocity	J:145846
	impaired balance	J:145846
	impaired coordination	J:145846
	postnatal growth retardation	J:145846
	postnatal lethality, complete penetrance	J:145846
	weight loss	J:145846
Nfasc^tm2Bhat/Nfasc^tm2Bhat Cnp^tm1(cre)Kan/Cnp⁺ involves: 129S1/Sv * 129X1/SvJ	abnormal paranodal axoglial junction morphology	J:159621
	abnormal paranode morphology	J:159621
	ataxia	J:159621
	impaired coordination	J:159621
	weight loss	J:159621
Pex5^tm1Pec/Pex5^tm1Pec Cnp^tm1(cre)Kan/Cnp⁺ involves: 129S1/Sv * 129X1/SvJ	abnormal axon morphology	J:123503
	abnormal brain white matter morphology	J:123503
	abnormal breathing pattern	J:123503
	abnormal glial cell morphology	J:123503
	abnormal inflammatory response	J:123503
	abnormal myelination	J:123503
	abnormal oligodendrocyte morphology	J:123503
	ataxia	J:123503
	gliosis	J:123503
	hindlimb paralysis	J:123503
	hindlimb paresis	J:123503
	kyphosis	J:123503
	microgliosis	J:123503
	premature death	J:123503
	tremors	J:123503
Plp1^{tm1c(EUCOMM)Wtsi}/Y Cnp^tm1(cre)Kan/Cnp⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6N	abnormal hippocampal fimbria morphology	J:245100
	astrocytosis	J:245100
	axonal spheroids	J:245100
	increased T cell number	J:245100
	microgliosis	J:245100
Plp1^tm1Kan/Y Cnp^tm1(cre)Kan/Cnp⁺ involves: 129S1/Sv * 129X1/SvJ	abnormal hippocampal fimbria morphology	J:245100
	astrocytosis	J:245100
	axonal spheroids	J:245100
	increased T cell number	J:245100
	microgliosis	J:245100
Pten^tm1Hwu/Pten^tm1Hwu Cnp^tm1(cre)Kan/Cnp⁺ involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ	abnormal brain white matter morphology	J:161841
	abnormal corpus callosum morphology	J:161841
	abnormal myelin sheath morphology	J:161841
	abnormal oligodendrocyte morphology	J:161841
	abnormal salivary gland morphology	J:161841
	abnormal Schwann cell morphology	J:161841
	abnormal sciatic nerve morphology	J:161841
	cataract	J:161841
	hypermyelination	J:161841
	increased brain size	J:161841
	megacolon	J:161841
	premature death	J:161841
	reduced fertility	J:161841
Septin2^{tm1c(EUCOMM)Wtsi}/Septin2^{tm1c(EUCOMM)Wtsi} Cnp^tm1(cre)Kan/Cnp⁺ involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6N	abnormal sciatic nerve morphology	J:339068
Septin9^tm2.1Emfu/Septin9^tm2.1Emfu Cnp^tm1(cre)Kan/Cnp⁺ involves: 129S1/Sv * 129X1/SvJ	normal nervous system phenotype	J:339068
Zfp24^tm1.1Pop/Zfp24^tm1.1Pop Cnp^tm1(cre)Kan/Cnp⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal myelin sheath morphology	J:156938
	tonic seizures	J:156938
	tremors	J:156938

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