Col11a2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Col11a2
collagen, type XI, alpha 2
MGI:88447

24 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Col11a2^{tm1b(KOMP)Wtsi}/Col11a2⁺ C57BL/6N-Col11a2^{tm1b(KOMP)Wtsi}/Ieg	decreased cardiac output	J:211773
	decreased circulating triglyceride level	J:211773
	decreased mean corpuscular volume	J:211773
	increased circulating bilirubin level	J:211773
	increased circulating unsaturated transferrin level	J:211773
	increased lean body mass	J:211773
	increased startle reflex	J:211773
Col11a2^{tm1b(KOMP)Wtsi}/Col11a2^{tm1b(KOMP)Wtsi} C57BL/6N-Col11a2^{tm1b(KOMP)Wtsi}/Ieg	preweaning lethality, incomplete penetrance	J:211773
Col11a2^tm1Mne/Col11a2^tm1Mne FVB.129-Col11a2^tm1Mne	abnormal articular cartilage morphology	J:71948
	abnormal chondrocyte morphology	J:71948
	abnormal cranium morphology	J:71948
	abnormal nasal bone morphology	J:71948
	abnormal tectorial membrane morphology	J:58794
	decreased body size	J:71948
	disorganized long bone epiphyseal plate	J:71948
	enlarged tectorial membrane	J:58794
	impaired hearing	J:58794, J:71948
	increased or absent threshold for auditory brainstem response	J:58794, J:71948
	nonsyndromic hearing loss	J:58794
	postnatal growth retardation	J:71948
	prominent forehead	J:71948
	sensorineural hearing loss	J:58794
	short snout	J:71948
	triangular face	J:71948

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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