Col11a2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Col11a2
collagen, type XI, alpha 2
MGI:88447

24 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Col11a2^{tm1b(KOMP)Wtsi}/Col11a2⁺ C57BL/6N-Col11a2^{tm1b(KOMP)Wtsi}/Ieg	decreased cardiac output	J:211773
	decreased circulating triglyceride level	J:211773
	decreased mean corpuscular volume	J:211773
	increased circulating bilirubin level	J:211773
	increased circulating unsaturated transferrin level	J:211773
	increased lean body mass	J:211773
	increased startle reflex	J:211773
Col11a2^{tm1b(KOMP)Wtsi}/Col11a2^{tm1b(KOMP)Wtsi} C57BL/6N-Col11a2^{tm1b(KOMP)Wtsi}/Ieg	preweaning lethality, incomplete penetrance	J:211773
Col11a2^tm1Mne/Col11a2^tm1Mne FVB.129-Col11a2^tm1Mne	abnormal articular cartilage morphology	J:71948
	abnormal chondrocyte morphology	J:71948
	abnormal cranium morphology	J:71948
	abnormal nasal bone morphology	J:71948
	abnormal tectorial membrane morphology	J:58794
	decreased body size	J:71948
	disorganized long bone epiphyseal plate	J:71948
	enlarged tectorial membrane	J:58794
	impaired hearing	J:58794, J:71948
	increased or absent threshold for auditory brainstem response	J:58794, J:71948
	nonsyndromic hearing loss	J:58794
	postnatal growth retardation	J:71948
	prominent forehead	J:71948
	sensorineural hearing loss	J:58794
	short snout	J:71948
	triangular face	J:71948

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24