Col17a1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Col17a1
collagen, type XVII, alpha 1
MGI:88450

43 phenotypes from 17 alleles in 18 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Col17a1^em1(IMPC)Mbp/Col17a1^em1(IMPC)Mbp C57BL/6N-Col17a1^em1(IMPC)Mbp/MbpMmucd	abnormal skin morphology	J:211773
	decreased circulating calcium level	J:211773
	decreased circulating serum albumin level	J:211773
	hydrometra	J:211773
	increased freezing behavior	J:211773
Col17a1^em1Dcr/Col17a1^em1Dcr C57BL/6J-Col17a1^em1Dcr/DcrJ	normal integument phenotype	J:352187
Col17a1^em2Dcr/Col17a1^em2Dcr C57BL/6J-Col17a1^em2Dcr/Dcr	spontaneous skin ulceration	J:352187
Col17a1^em4Dcr/Col17a1^em4Dcr C57BL/6J-Col17a1^em4Dcr/Dcr	abnormal skin tensile strength	J:352187
Col17a1^em5Dcr/Col17a1^em5Dcr C57BL/6J-Col17a1^em5Dcr/Dcr	abnormal skin tensile strength	J:352187
Col17a1^em7Dcr/Col17a1^em7Dcr C57BL/6J-Col17a1^em7Dcr/Dcr	abnormal skin tensile strength	J:352187
Col17a1^em8Dcr/Col17a1^em8Dcr C57BL/6J-Col17a1^em8Dcr/DcrJ	abnormal cornea morphology	J:352187
	abnormal nail bed morphology	J:352187
	dermal-epidermal separation	J:352187
	premature death	J:352187
Col17a1^em9Dcr/Col17a1^em9Dcr C57BL/6J-Col17a1^em9Dcr/Dcr	abnormal skin tensile strength	J:352187
Col17a1^em10Dcr/Col17a1^em10Dcr C57BL/6J-Col17a1^em10Dcr/Dcr	normal integument phenotype	J:352187
Col17a1^em13Dcr/Col17a1^em13Dcr C57BL/6J-Col17a1^em13Dcr/Dcr	normal integument phenotype	J:352187
Col17a1^em14Dcr/Col17a1^em14Dcr C57BL/6J-Col17a1^em14Dcr/Dcr	normal integument phenotype	J:352187
Col17a1^em15Dcr/Col17a1^em15Dcr C57BL/6J-Col17a1^em15Dcr/Dcr	spontaneous skin ulceration	J:352187
Col17a1^em16Dcr/Col17a1^em16Dcr C57BL/6J-Col17a1^em16Dcr/Dcr	normal integument phenotype	J:352187
Col17a1^em17Dcr/Col17a1^em17Dcr C57BL/6J-Col17a1^em17Dcr/Dcr	normal integument phenotype	J:352187
Col17a1^em18Dcr/Col17a1^em18Dcr C57BL/6J-Col17a1^em18Dcr/Dcr	normal integument phenotype	J:352187
Col17a1^tm1Shzu/Col17a1^tm1Shzu B6.129S-Col17a1^tm1Shzu	abnormal epidermal layer morphology	J:121695
	abnormal fertility/fecundity	J:121695
	abnormal skin condition	J:121695
	blistering	J:121695
	postnatal growth retardation	J:121695
	postnatal lethality, incomplete penetrance	J:121695
	sparse hair	J:121695
Col17a1^tm1Tiin/Col17a1^tm1Tiin involves: C57BL/6	abnormal basement membrane morphology	J:220622
	abnormal coat/hair pigmentation	J:220622
	abnormal epidermal-dermal junction morphology	J:220622
	abnormal skin morphology	J:220622
	blistering	J:220622
	excessive scratching	J:220622
	focal hair loss	J:220622
	hyperkeratosis	J:220622
	increased autoantibody level	J:220622
	increased basophil cell number	J:220622
	increased eosinophil cell number	J:220622
	increased fibroblast proliferation	J:220622
	increased IgE level	J:220622
	increased monocyte cell number	J:220622
	increased neutrophil cell number	J:220622
	increased pruritus	J:220622
	skin inflammation	J:220622
	skin lesions	J:220622
	sparse hair	J:220622
	thick epidermis	J:220622
Col17a1^tm1Tiin/Col17a1^tm1Tiin involves: C57BL/6JOlaHsd	abnormal hair growth	J:219481
	abnormal podocyte morphology	J:219481
	abnormal renal glomerulus basement membrane morphology	J:219481
	abnormal renal glomerulus morphology	J:219481
	blistering	J:219481
	decreased body size	J:219481
	focal hair loss	J:219481
	podocyte foot process effacement	J:219481
	podocyte hypertrophy	J:219481
	postnatal growth retardation	J:219481
	postnatal lethality, incomplete penetrance	J:219481

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