Col3a1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Col3a1
collagen, type III, alpha 1
MGI:88453

32 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Col3a1^m1Btlr/Col3a1^m1Btlr C57BL/6J-Col3a1^m1Btlr	increased alpha-beta T cell number	J:271973
	increased CD4-positive, alpha-beta T cell number	J:271973
	increased CD8-positive, alpha-beta T cell number	J:271973
	increased susceptibility to induced colitis	J:271973
Col3a1^m1Lsmi/Col3a1⁺ involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J	aortic dissection	J:180733
	premature death	J:180733
Col3a1^m1Lsmi/Col3a1⁺ involves: 129P2/OlaHsd * C3H/HeH * C57BL/6J	aortic dissection	J:180733
	premature death	J:180733
Col3a1^m1Lsmi/Col3a1⁺ involves: 129P2/OlaHsd * C57BL/6J	abnormal aorta elastic tissue morphology	J:180733
	abnormal aorta smooth muscle morphology	J:180733
	abnormal response/metabolism to endogenous compounds	J:180733
	aortic dissection	J:180729, J:180733
	increased systemic arterial systolic blood pressure	J:180733
	increased vasoconstriction	J:180733
	premature death	J:180729, J:180733
Col3a1^m1Lsmi/Col3a1^m1Lsmi involves: 129P2/OlaHsd * C57BL/6J	embryonic lethality, complete penetrance	J:180729, J:180733
Col3a1^tm1Jae/Col3a1^tm1Jae involves: 129S4/SvJae	abnormal aorta wall morphology	J:39273
	abnormal blood vessel morphology	J:39273
	abnormal cutaneous collagen fibril morphology	J:39273
	abnormal intestine morphology	J:39273
	abnormal liver morphology	J:39273
	abnormal lung morphology	J:39273
	abnormal subendocardium layer morphology	J:39273
	normal cardiovascular system phenotype	J:39273
	decreased body size	J:39273
	normal muscle phenotype	J:39273
	postnatal lethality, incomplete penetrance	J:39273
	premature death	J:39273
	skin lesions	J:39273
Col3a1^Tsk2/Col3a1⁺ C3H101H-Col3a1^Tsk2/H	abnormal skin morphology	J:31216, J:215227
	adipose tissue inflammation	J:31216
	normal cellular phenotype	J:55591
	skin fibrosis	J:31216
	skin inflammation	J:31216
	thick dermal layer	J:31216
	tight skin	J:14073, J:31216
Col3a1^Tsk2/Col3a1^Tsk2 C3H101H-Col3a1^Tsk2/H	prenatal lethality, complete penetrance	J:14073

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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