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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Col4a5
collagen, type IV, alpha 5
MGI:88456
51 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Col4a5em1Keha/Y
C57BL/6J-Col4a5em1Keha 		abnormal renal glomerular capsule morphology J:283613
abnormal renal glomerulus basement membrane morphology J:283613
abnormal renal glomerulus morphology J:283613
albuminuria J:283613
decreased body weight J:283613
decreased circulating total protein level J:283613
expanded mesangial matrix J:283613
glomerulosclerosis J:283613
hematuria J:283613
increased blood urea nitrogen level J:283613
increased circulating creatinine level J:283613
increased renal glomerulus basement membrane thickness J:283613
podocyte foot process effacement J:283613
premature death J:283613
renal interstitial fibrosis J:283613
Col4a5tm1b(EUCOMM)Wtsi/Y
C57BL/6N-Col4a5tm1b(EUCOMM)Wtsi/Cnrm 		abnormal kidney morphology J:211773
abnormal lens morphology J:211773
decreased circulating fructosamine level J:211773
decreased circulating serum albumin level J:211773
decreased circulating total protein level J:211773
decreased erythrocyte cell number J:211773
decreased hematocrit J:211773
decreased hemoglobin content J:211773
decreased mean corpuscular hemoglobin J:211773
decreased mean corpuscular volume J:211773
increased blood urea nitrogen level J:211773
increased circulating amylase level J:211773
increased circulating calcium level J:211773
increased circulating cholesterol level J:211773
increased circulating creatinine level J:211773
increased circulating triglyceride level J:211773
increased leukocyte cell number J:211773
persistence of hyaloid vascular system J:211773
thrombocytosis J:211773
Col4a5tm1b(EUCOMM)Wtsi/Col4a5tm1b(EUCOMM)Wtsi
C57BL/6N-Col4a5tm1b(EUCOMM)Wtsi/Cnrm 		abnormal kidney morphology J:211773
decreased circulating fructosamine level J:211773
decreased circulating serum albumin level J:211773
decreased circulating total protein level J:211773
decreased erythrocyte cell number J:211773
decreased hematocrit J:211773
decreased hemoglobin content J:211773
decreased total body fat amount J:211773
impaired glucose tolerance J:211773
increased blood urea nitrogen level J:211773
increased circulating amylase level J:211773
increased circulating calcium level J:211773
increased circulating cholesterol level J:211773
increased circulating creatinine level J:211773
increased circulating HDL cholesterol level J:211773
increased circulating phosphate level J:211773
increased circulating triglyceride level J:211773
increased large unstained cell number J:211773
increased neutrophil cell number J:211773
increased red blood cell distribution width J:211773
increased spleen weight J:211773
thrombocytosis J:211773
Col4a5tm1Yseg/Col4a5+
B6.Cg-Col4a5tm1Yseg 		abnormal eye physiology J:210414
abnormal kidney morphology J:102306
abnormal lens capsule morphology J:210414
abnormal renal glomerulus morphology J:102306
abnormal renal tubule morphology J:102306
increased blood urea nitrogen level J:102306
increased urine protein level J:102306
pale kidney J:102306
premature death J:102306
Col4a5tm1Yseg/Y
B6.Cg-Col4a5tm1Yseg 		abnormal eye physiology J:210414
abnormal glomerular capillary morphology J:102306
abnormal kidney morphology J:102306
abnormal lens capsule morphology J:210414
abnormal renal glomerulus basement membrane morphology J:102306
abnormal renal glomerulus morphology J:102306
dilated glomerular capillary J:102306
dilated renal tubule J:102306
glomerulosclerosis J:102306
increased blood urea nitrogen level J:102306
increased mesangial cell number J:102306
increased urine protein level J:102306
pale kidney J:102306
podocyte foot process effacement J:102306
premature death J:102306
renal glomerular synechia J:102306
renal tubule atrophy J:102306
tubulointerstitial nephritis J:102306
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory