Col6a1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Col6a1
collagen, type VI, alpha 1
MGI:88459

25 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Col6a1^tm1Gmb/Col6a1⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal diaphragm morphology	J:51410
	abnormal intercostal muscle morphology	J:51410
	centrally nucleated skeletal muscle fibers	J:51410
	myopathy	J:51410
	skeletal muscle necrosis	J:51410
Col6a1^tm1Gmb/Col6a1^tm1Gmb involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal diaphragm morphology	J:51410
	abnormal intercostal muscle morphology	J:51410
	abnormal muscle morphology	J:51410
	abnormal skeletal muscle morphology	J:86734
	impaired skeletal muscle contractility	J:86734
	normal muscle phenotype	J:51410
	myopathy	J:51410
	skeletal muscle necrosis	J:51410
Col6a1^tm1Sngi/Col6a1^tm1Sngi B6.Cg-Col6a1^tm1Sngi	abnormal locomotor behavior	J:278926
	abnormal muscle development	J:278926
	abnormal response to injury	J:278926
	abnormal skeletal muscle fiber morphology	J:278926
	abnormal skeletal muscle morphology	J:278926
	decreased body size	J:278926
	decreased body weight	J:278926
	decreased circulating insulin-like growth factor I level	J:278926
	decreased grip strength	J:278926
	decreased skeletal muscle fiber number	J:278926
	decreased skeletal muscle mass	J:278926
	decreased skeletal muscle size	J:278926
	impaired glucose tolerance	J:278926
	impaired skeletal muscle contractility	J:278926
	increased variability of skeletal muscle fiber size	J:278926
	muscle weakness	J:278926
	skeletal muscle endomysial fibrosis	J:278926
	normal skeleton phenotype	J:278926

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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