Col7a1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Col7a1
collagen, type VII, alpha 1
MGI:88462

19 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Col7a1^em#Jtol/Col7a1^em#Jtol involves: 129S4/SvJae * BALB/c * C57BL/Ka * NOD	absent B cells	J:280214
	absent NK T cells	J:280214
	absent T cells	J:280214
	blistering	J:280214
Col7a1^tm1.1Lbt/Col7a1^tm1.1Lbt involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	no abnormal phenotype detected	J:136145
Col7a1^tm1Lbt/Col7a1^tm1Lbt involves: 129S1/Sv * 129X1/SvJ * C57BL/6Crl	abnormal autopod morphology	J:136145
	abnormal dermal layer morphology	J:136145
	abnormal digit morphology	J:136145
	abnormal epidermal layer morphology	J:136145
	abnormal long bone morphology	J:136145
	abnormal nail morphology	J:136145
	abnormal tongue morphology	J:136145
	blistering	J:136145
	decreased bone mineral content	J:136145
	decreased survivor rate	J:136145
	dermal-epidermal separation	J:136145
	postnatal lethality	J:136145
	slow postnatal weight gain	J:136145
	thick epidermis	J:136145
Col7a1^tm1Uit/Col7a1^tm1Uit involves: 129S1/Sv	dermal-epidermal separation	J:155326
Col7a1^tm1Uit/Col7a1^tm1Uit involves: 129S1/Sv	postnatal lethality, complete penetrance	J:155326
Col7a1^tm1Uit/Col7a1^tm1Uit involves: 129S1/Sv * C57BL/6J	abnormal dermal layer morphology	J:58533
	blistering	J:58533
	postnatal lethality, complete penetrance	J:58533

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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