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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Cpa3
carboxypeptidase A3, mast cell
MGI:88479
17 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cpa3tm3(icre)Hrr/Cpa3+
Notch1tm1Agt/Notch1tm1Agt
involves: 129 * C57BL/6 		abnormal B cell differentiation J:143731
abnormal B cell morphology J:143731
abnormal T cell receptor beta chain V(D)J recombination J:143731
decreased double-negative T cell number J:143731
decreased double-positive T cell number J:143731
increased single-positive T cell number J:143731
thymus hypoplasia J:143731
Cpa3tm3(icre)Hrr/Cpa3+
Fgfr1tm1Upir/Fgfr1tm1Upir
Fgfr2tm1Dor/Fgfr2tm1Dor
Tg(KRT5-cre)5132Jlj/0
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J 		absent mast cells J:221184
acanthosis J:221184
decreased body weight J:221184
female infertility J:221184
impaired skin barrier function J:221184
increased keratinocyte proliferation J:221184
progressive hair loss J:221184
reduced male fertility J:221184
skin inflammation J:221184
Cpa3tm3(icre)Hrr/Cpa3+
Gt(ROSA)26Sortm1Hjf/?
Notch1tm1Agt/Notch1tm1Agt
involves: 129 * C57BL/6 		abnormal dendritic cell differentiation J:143731
abnormal T cell receptor beta chain V(D)J recombination J:143731
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory