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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Crem
cAMP responsive element modulator
MGI:88495
26 phenotypes from 5 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cremtm1.1Endo/Cremtm1.1Endo
C57BL/6-Cremtm1.1Endo 		abnormal contextual conditioning behavior J:137666
abnormal cued conditioning behavior J:137666
abnormal kindling response J:137666
normal behavior/neurological phenotype J:137666
increased anxiety-related response J:137666
Cremtm1Gsc/Cremtm1Gsc
involves: 129 * C57BL/6 		arrest of male meiosis J:31889
decreased heart left ventricle muscle contractility J:81241
male infertility J:31889
small testis J:31889
Cremtm1Saco/Crem+
involves: 129/Sv * C57BL/6 		oligozoospermia J:31889
reduced male fertility J:31889
teratozoospermia J:31889
Cremtm1Saco/Cremtm1Saco
involves: 129/Sv * C57BL/6 		abnormal circadian behavior J:58568
arrest of spermatogenesis J:31890
decreased anxiety-related response J:58568
decreased testis weight J:31890
hyperactivity J:58568
impaired liver regeneration J:81370
male infertility J:31890
multinucleated giant male germ cells J:81370
small seminiferous tubules J:31890
Cremtm1Saco/Cremtm1Saco
involves: C57BL/6 		arrest of spermatogenesis J:88151
male infertility J:88151
Tg(Camk2a-Crem)I15Endo/0
involves: C3H * C57BL/6 		abnormal contextual conditioning behavior J:137666
abnormal cued conditioning behavior J:137666
abnormal kindling response J:137666
normal behavior/neurological phenotype J:137666
decreased exploration in new environment J:137666
decreased locomotor activity J:137666
impaired coordination J:137666
Tg(Camk2a-Crem)IIEndo/0
C57BL/6-Tg(Camk2a-Crem)IIEndo/EndoRbrc 		abnormal cued conditioning behavior J:137666
abnormal kindling response J:137666
abnormal touch/ nociception J:137666
normal behavior/neurological phenotype J:137666
decreased body weight J:137666
increased startle reflex J:137666
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory