Cr1l Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cr1l
complement C3b/C4b receptor 1 like
MGI:88513

21 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cr1l^tm1.1Song/Cr1l^tm1.1Song Tg(Cd4-cre)1Cwi/0 involves: 129S6/SvEvTac * C57BL/6 * DBA/2 * SJL	decreased CD4-positive, alpha-beta T cell number	J:146538
	decreased CD8-positive, alpha-beta T cell number	J:146538
	decreased lymphocyte cell number	J:146538
	increased B cell number	J:146538
	lymph node hypoplasia	J:146538
Cr1l^tm1.1Song/Cr1l^tm1.1Song Tg(Lck-cre)548Jxm/0 involves: 129S6/SvEvTac * C57BL/6 * DBA/2 * SJL	decreased CD4-positive, alpha-beta T cell number	J:146538
	decreased CD8-positive, alpha-beta T cell number	J:146538
	decreased lymphocyte cell number	J:146538
	increased B cell number	J:146538
	lymph node hypoplasia	J:146538
Cr1l^{tm1b(KOMP)Wtsi}/Cr1l⁺ B6N(Cg)-Cr1l^{tm1b(KOMP)Wtsi}/J	abnormal retina blood vessel morphology	J:211773
Cr1l^{tm1b(KOMP)Wtsi}/Cr1l^{tm1b(KOMP)Wtsi} B6N(Cg)-Cr1l^{tm1b(KOMP)Wtsi}/J	embryonic growth retardation	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Cr1l^tm1Hmo/Cr1l⁺ involves: 129X1/SvJ	abnormal proximal convoluted tubule morphology	J:105466
	increased blood urea nitrogen level	J:105466
	increased susceptibility to kidney reperfusion injury	J:105466
Cr1l^tm1Hmo/Cr1l^tm1Hmo involves: 129X1/SvJ	abnormal ectoplacental cone morphology	J:59432
	abnormal hippocampus morphology	J:197576
	abnormal maternal decidual layer morphology	J:59432
	abnormal trophectoderm morphology	J:59432
	increased inflammatory response	J:59432
	lethality throughout fetal growth and development, complete penetrance	J:59432
	normal mortality/aging	J:197576
Tg(Mt1-Crry)26Quig/? involves: CD-1	abnormal inflammatory response	J:117777
Tg(Mt1-Crry)26Quig/? involves: CD-1	abnormal kidney physiology	J:117777

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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