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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Csnk2b
casein kinase 2, beta polypeptide
MGI:88548
39 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Csnk2btm1.1Bb/Csnk2btm1.1Bb
Tg(ACTA1-cre)79Jme/?
involves: 129S2/SvPasCrl * C57BL/6J * SJL 		abnormal miniature endplate potential J:110237
abnormal neuromuscular synapse morphology J:110237
decreased body weight J:110237
decreased grip strength J:110237
Csnk2btm1.1Bb/Csnk2btm1.1Bb
Tg(Gdf9-icre)5092Coo/0
involves: 129S2/SvPasCrl * C57BL/6 		abnormal double-strand DNA break repair J:305036
absent primary ovarian follicles J:305036
absent primordial ovarian follicles J:305036
absent secondary ovarian follicles J:305036
absent tertiary ovarian follicles J:305036
decreased oocyte number J:305036
decreased ovary weight J:305036
decreased primordial ovarian follicle number J:305036
decreased secondary ovarian follicle number J:305036
decreased tertiary ovarian follicle number J:305036
female infertility J:305036
increased atretic ovarian follicle number J:305036
increased granulosa cell apoptosis J:305036
ovary atrophy J:305036
premature ovarian failure J:305036
Csnk2btm1.1Bb/Csnk2btm1.2Bb
Tg(Stra8-icre)1Reb/0
involves: 129S2/SvPasCrl * C57BL/6 * FVB/NJ 		abnormal protein level J:289955
abnormal seminiferous tubule morphology J:289955
abnormal spermatid morphology J:289955
abnormal spermatocyte morphology J:289955
arrest of spermatogenesis J:289955
azoospermia J:289955
decreased male germ cell number J:289955
decreased testis weight J:289955
increased male germ cell apoptosis J:289955
increased testis apoptosis J:289955
male infertility J:289955
small seminiferous tubules J:289955
small testis J:289955
testicular atrophy J:289955
Csnk2btm1.2Bb/Csnk2btm1.2Bb
involves: 129S2/SvPasCrl * C57BL/6 		abnormal trophoblast giant cell morphology J:81637
absent inner cell mass J:81637
decreased embryo size J:81637
embryonic growth arrest J:81637
embryonic growth retardation J:81637
embryonic lethality between implantation and somite formation, complete penetrance J:81637
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory