Ctsl Phenotype Annotations - Multigenic Genotypes

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ctsl
cathepsin L
MGI:88564

17 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ctsb^tm1Jde/Ctsb^tm1Jde Ctsl^tm1Cptr/Ctsl^tm1Cptr involves: 129P2/OlaHsd * C57BL/6J	abnormal hippocampus pyramidal cell layer	J:77103
	abnormal motor coordination/balance	J:77103
	abnormal neuron apoptosis	J:77103
	decreased vertical activity	J:77103
	delayed hair appearance	J:77103
	gliosis	J:77103
	neuron degeneration	J:77103
	postnatal growth retardation	J:77103
	postnatal lethality, incomplete penetrance	J:77103
	Purkinje cell degeneration	J:77103
	thick epidermis	J:77103
	tremors	J:77103
Ctsk^tm1Psa/Ctsk^tm1Psa Ctsl^tm1Cptr/Ctsl^tm1Cptr involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6J	abnormal thyroid follicle morphology	J:83877
	abnormal thyroid gland morphology	J:83877
	abnormal thyroid hormone level	J:83877
	decreased circulating thyroxine level	J:83877
	decreased thyroxine level	J:83877

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24