Cux1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cux1
cut-like homeobox 1
MGI:88568

51 phenotypes from 4 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cux1^tm1Ejn/Cux1^tm1Ejn B6;129S4-Cux1^tm1Ejn/J	normal renal/urinary system phenotype	J:142805
Cux1^tm1Ejn/Cux1^tm1Ejn C.129S4-Cux1^tm1Ejn	postnatal lethality, incomplete penetrance	J:90149
	premature death	J:90149
	reduced fertility	J:90149
Cux1^tm1Ejn/Cux1^tm1Ejn involves: 129S4/SvJae * C57BL	abnormal hair follicle orientation	J:49157
	abnormal maternal behavior	J:49157
	curly vibrissae	J:49157
	darkened coat color	J:49157
	kinked vibrissae	J:49157
Cux1^tm1Mbu/Cux1^tm1Mbu involves: 129P2/OlaHsd * C57BL/6	abnormal alveolocapillary membrane morphology	J:71407
	abnormal hair follicle morphology	J:71407
	abnormal hair follicle orientation	J:71407
	abnormal hair shaft morphology	J:71407
	abnormal lung development	J:71407
	abnormal lung morphology	J:71407
	abnormal pulmonary alveolar duct morphology	J:71407
	absent auchene hairs	J:71407
	absent awl hair	J:71407
	absent guard hair	J:71407
	absent hair follicle inner root sheath	J:71407
	absent zigzag hairs	J:71407
	curly vibrissae	J:71407
	cyanosis	J:71407
	neonatal lethality, incomplete penetrance	J:71407
	postnatal growth retardation	J:71407
	short vibrissae	J:71407
	sparse hair	J:71407
Cux1^tm1Mbu/Cux1^tm1Mbu involves: C3H/He	neonatal lethality, incomplete penetrance	J:71407
Cux1^tm1Mbu/Cux1^tm1Mbu involves: C3H/He	respiratory failure	J:71407
Cux1^tm1Mbu/Cux1^tm1Mbu involves: OF1	abnormal coat/ hair morphology	J:71407
	abnormal hair follicle morphology	J:71407
	abnormal hair follicle orientation	J:71407
	absent auchene hairs	J:71407
	absent awl hair	J:71407
	absent guard hair	J:71407
	absent hair follicle inner root sheath	J:71407
	absent zigzag hairs	J:71407
	curly vibrissae	J:71407
	normal mortality/aging	J:71407
	postnatal growth retardation	J:71407
	normal reproductive system phenotype	J:71407
	short vibrissae	J:71407
	sparse hair	J:71407
Cux1^tm1Rhsc/Cux1^tm1Rhsc involves: 129S1/Sv * C57BL/6J	abnormal bone structure	J:100055
	abnormal hair follicle morphology	J:100055
	abnormal myelopoiesis	J:100055
	abnormal T cell differentiation	J:100055
	abnormal tumor necrosis factor level	J:100055
	alopecia	J:100055
	cachexia	J:100055
	decreased B cell number	J:100055
	decreased body size	J:100055
	decreased double-positive T cell number	J:100055
	decreased thymocyte number	J:100055
	decreased total body fat amount	J:100055
	increased hair follicle number	J:100055
	neonatal lethality, incomplete penetrance	J:100055
	postnatal growth retardation	J:100055
	premature death	J:100055
	small thymus	J:100055
	thymus cortex hypoplasia	J:100055
	thymus hypoplasia	J:100055
	wavy vibrissae	J:100055
Cux1^tm2Ejn/Cux1⁺ involves: 129S4/SvJae * C57BL/6	decreased circulating testosterone level	J:74660
Cux1^tm2Ejn/Cux1^tm2Ejn C.129S4-Cux1^tm2Ejn	postnatal lethality, incomplete penetrance	J:90149
Cux1^tm2Ejn/Cux1^tm2Ejn involves: 129S4/SvJae * C57BL/6	alopecia	J:74660
	decreased circulating testosterone level	J:74660
	enlarged hair follicles	J:74660
	increased susceptibility to bacterial infection	J:74660
	postnatal growth retardation	J:74660
	postnatal lethality	J:74660
	reduced male fertility	J:74660
	rhinitis	J:74660

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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