About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
MGI:88586
29 phenotypes from 3 alleles in 3 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Cyp17a1tm1b(EUCOMM)Wtsi/Cyp17a1tm1b(EUCOMM)Wtsi
C57BL/6N-Cyp17a1tm1b(EUCOMM)Wtsi/Nju 		abnormal auditory brainstem response J:211773
abnormal bone structure J:211773
abnormal male genitalia morphology J:211773
abnormal vocalization J:211773
absent external male genitalia J:211773
decreased bone mineral content J:211773
decreased bone mineral density J:211773
decreased circulating phosphate level J:211773
decreased grip strength J:211773
decreased heart weight J:211773
decreased lean body mass J:211773
decreased locomotor activity J:211773
improved glucose tolerance J:211773
increased blood urea nitrogen level J:211773
increased circulating alkaline phosphatase level J:211773
increased circulating cholesterol level J:211773
increased circulating creatinine level J:211773
increased circulating HDL cholesterol level J:211773
increased fasting circulating glucose level J:211773
increased total body fat amount J:211773
Cyp17a1tm1Mell/Cyp17a1tm1Mell
involves: 129X1/SvJ * C57BL/6 		embryonic lethality between implantation and somite formation, complete penetrance J:91081
Cyp17a1tm1Vpap/Cyp17a1+
chimera involves: 129X1/SvJ * C57BL/6 		abnormal sexual interaction J:100434
abnormal sperm flagellum morphology J:100434
abnormal testosterone level J:100434
asthenozoospermia J:100434
decreased circulating testosterone level J:100434
early reproductive senescence J:100434
reduced male fertility J:100434
transmission ratio distortion J:100434
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory