Cyp1b1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
MGI:88590

8 phenotypes from 1 allele in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cyp1b1^tm1Gonz/Cyp1b1^tm1Gonz 129X1.Cg-Cyp1b1^tm1Gonz	abnormal canal of Schlemm morphology	J:82280
	abnormal iridocorneal angle	J:82280
	hypoplastic trabecular meshwork	J:82280
Cyp1b1^tm1Gonz/Cyp1b1^tm1Gonz B6.Cg-Cyp1b1^tm1Gonz	abnormal canal of Schlemm morphology	J:82280
	abnormal iridocorneal angle	J:82280
	hypoplastic trabecular meshwork	J:82280
Cyp1b1^tm1Gonz/Cyp1b1^tm1Gonz involves: 129X1/SvJ * C57BL/6	decreased physiological sensitivity to xenobiotic	J:81113
Cyp1b1^tm1Gonz/Cyp1b1^tm1Gonz involves: 129X1/SvJ * C57BL/6J	abnormal iridocorneal angle	J:82280
	abnormal trabecular meshwork morphology	J:82280
	absent Schlemm's canal	J:82280
	anterior iris synechia	J:82280
Cyp1b1^tm1Gonz/Cyp1b1^tm1Gonz involves: 129X1/SvJ * C57BL/6N	decreased incidence of tumors by chemical induction	J:53827

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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