Ccn1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ccn1
cellular communication network factor 1
MGI:88613

26 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ccn1^tm1Lfl/Ccn1⁺ involves: 129S4/SvJae * C57BL/6J	abnormal interventricular septum morphology	J:126490
	abnormal mitral valve morphology	J:126490
	complete atrioventricular septal defect	J:126490
	ostium primum atrial septal defect	J:126490
	patent cardiac foramen ovale	J:126490
	ventricular septal defect	J:126490
Ccn1^tm1Lfl/Ccn1^tm1Lfl involves: 129S4/SvJae * C57BL/6J	abnormal apoptosis	J:80618
	abnormal artery morphology	J:80618
	abnormal chorionic plate morphology	J:80618
	abnormal dorsal aorta morphology	J:80618
	abnormal heart development	J:126490
	abnormal interventricular septum morphology	J:126490
	abnormal placenta morphology	J:80618
	abnormal placental labyrinth vasculature morphology	J:80618
	common atrioventricular valve	J:126490
	complete atrioventricular septal defect	J:126490
	dilated dorsal aorta	J:80618
	embryonic lethality during organogenesis, incomplete penetrance	J:80618
	failure of atrioventricular cushion closure	J:126490
	failure of chorioallantoic fusion	J:80618
	hemorrhage	J:80618
	neonatal lethality, complete penetrance	J:80618
	pale placenta	J:80618
	ventricular septal defect	J:126490
Ccn1^tm3.1Lfl/Ccn1^tm3.1Lfl Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ involves: 129S4/SvJae * C57BL/6 * DBA	abnormal cellular replicative senescence	J:204032
	increased susceptibility to injury	J:204032
	liver fibrosis	J:204032
	normal liver/biliary system phenotype	J:204032
Tg(Alb-Cyr61)#Lfl/0 involves: C57BL/6	decreased susceptibility to injury	J:204032

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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