Adarb1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Adarb1
adenosine deaminase, RNA-specific, B1
MGI:891999

23 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Adarb1^tm1.1Eme/Adarb1^tm1.1Eme involves: 129S6/SvEvTac * C57BL/6J	no abnormal phenotype detected	J:144148
Adarb1^tm1.1Skwa/Adarb1^tm1.1Skwa Tg(SLC18A3-cre)KMisa/0 involves: C57BL/6	abnormal cranial nerve morphology	J:164294
	abnormal facial nerve morphology	J:164294
	abnormal hypoglossal nerve morphology	J:164294
	abnormal innervation	J:164294
	abnormal limb posture	J:164294
	abnormal neuromuscular synapse morphology	J:164294
	abnormal posture	J:164294
	abnormal skeletal muscle fiber morphology	J:164294
	abnormal ventral spinal root morphology	J:164294
	normal behavior/neurological phenotype	J:164294
	centrally nucleated skeletal muscle fibers	J:164294
	decreased body weight	J:164294
	decreased grip strength	J:164294
	decreased locomotor activity	J:164294
	decreased spinal cord ventral horn cell number	J:164294
	impaired coordination	J:164294
	motor neuron degeneration	J:164294
	premature death	J:164294
	skeletal muscle fiber atrophy	J:164294
Adarb1^tm1Phs/Adarb1^tm1Phs involves: 129S1/Sv * 129X1/SvJ	abnormal AMPA-mediated synaptic currents	J:63273
	postnatal lethality, complete penetrance	J:63273
	seizures	J:63273

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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