Agrp Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Agrp
agouti related neuropeptide
MGI:892013

28 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Agrp^tm1Dgen/Agrp^tm1Dgen involves: 129P2/OlaHsd * C57BL/6	abnormal liver physiology	J:199803
	normal adipose tissue phenotype	J:199803
	normal behavior/neurological phenotype	J:199803
	decreased circulating ketone body level	J:199803
	decreased circulating VLDL triglyceride level	J:199803
	decreased lean body mass	J:199803
	decreased liver triglyceride level	J:199803
	normal growth/size/body region phenotype	J:199803
	normal homeostasis/metabolism phenotype	J:199803
	increased noradrenaline level	J:199803
	increased susceptibility to weight loss	J:199803
Agrp^tm1Mws/Agrp^tm1Mws B6.129S1-Agrp^tm1Mws	abnormal blood homeostasis	J:117539
	abnormal energy expenditure	J:117539
	normal behavior/neurological phenotype	J:117539
	decreased body weight	J:117539
	decreased cholesterol level	J:117539
	decreased circulating leptin level	J:117539
	decreased respiratory quotient	J:117539
	decreased total body fat amount	J:117539
	hyperactivity	J:117539
	increased circulating thyroxine level	J:117539
	increased circulating triiodothyronine level	J:117539
	increased core body temperature	J:117539
Agrp^tm1Mws/Agrp^tm1Mws involves: 129S1/Sv * C57BL/6J	abnormal food intake	J:117539
Agrp^tm1Mws/Agrp^tm1Mws involves: 129S1/Sv * C57BL/6J	normal growth/size/body region phenotype	J:117539
Agrp^tm1Sqn/Agrp^tm1Sqn involves: 129S7/SvEvBrd	no abnormal phenotype detected	J:78034
Agrp^tm1Sqn/Agrp^tm1Sqn involves: 129S7/SvEvBrd * C57BL/6J	abnormal energy expenditure	J:116654
	decreased lean body mass	J:116654
	extended life span	J:116654
	impaired adaptive thermogenesis	J:116654
	increased body weight	J:116654
	increased food intake	J:116654

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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