Sfrp1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sfrp1
secreted frizzled-related protein 1
MGI:892014

19 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Dkk1^tm1Sia/Dkk1^tm1Sia Sfrp1^tm1Aksh/Sfrp1^tm1Aksh involves: 129 * C57BL/6 * CBA	incomplete somite formation	J:135313
Dkk1^tm1Sia/Dkk1^tm1Sia Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2⁺ involves: 129 * C57BL/6 * CBA	incomplete somite formation	J:135313
Dkk1^tm1Sia/Dkk1^tm1Sia Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2^tm1Aksh involves: 129 * C57BL/6 * CBA	abnormal presomitic mesoderm morphology	J:135313
	incomplete embryo turning	J:135313
	incomplete somite formation	J:135313
Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2⁺ Sfrp5^tm1Aksh/Sfrp5^tm1Aksh Vangl2^Lp/Vangl2⁺ involves: 129 * A * C57BL/6 * LPT/LeJ	spina bifida	J:135313
Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2^tm1Aksh involves: 129 * C57BL/6	abnormal craniofacial morphology	J:106551
	abnormal rostral-caudal axis patterning	J:106551, J:135313
	abnormal rostral-caudal body axis extension	J:106551
	abnormal somite development	J:106551
	decreased somite size	J:106551
	decreased thoracic vertebrae number	J:106551
	edema	J:106551
	incomplete somite formation	J:106551, J:135313
	lethality throughout fetal growth and development, complete penetrance	J:106551
	short limbs	J:106551
	syndactyly	J:106551
Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2^tm1Aksh Sfrp5^tm1Aksh/Sfrp5⁺ involves: 129 * C57BL/6	abnormal rostral-caudal axis patterning	J:135313
	abnormal somite development	J:135313
Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2^tm1Aksh Sfrp5^tm1Aksh/Sfrp5⁺ Vangl2^Lp/Vangl2⁺ involves: 129 * A * C57BL/6 * LPT/LeJ	abnormal rostral-caudal body axis extension	J:135313
	abnormal somite development	J:135313
	craniorachischisis	J:135313
	open neural tube	J:135313
Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2^tm1Aksh Sfrp5^tm1Aksh/Sfrp5^tm1Aksh involves: 129 * C57BL/6	abnormal rostral-caudal axis patterning	J:135313
	decreased somite size	J:135313
	embryonic growth retardation	J:135313
	embryonic lethality, complete penetrance	J:135313
	fused somites	J:135313
	incomplete somite formation	J:135313
	open neural tube	J:135313
Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp5^tm1Aksh/Sfrp5^tm1Aksh Vangl2^Lp/Vangl2⁺ involves: 129 * A * C57BL/6 * LPT/LeJ	spina bifida	J:135313

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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