Pld2 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pld2
phospholipase D2
MGI:892877

11 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Pld1^tm1.1Mafr/Pld1^tm1.1Mafr Pld2^tm1Yaka/Pld2^tm1Yaka involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj	no abnormal phenotype detected	J:192844
Pld1^tm3Mafr/Pld1^tm3Mafr Pld2^{tm1(KOMP)Vlcg}/Pld2^{tm1(KOMP)Vlcg} involves: C57BL/6 * C57BL/6NTac	abnormal enzyme/coenzyme activity	J:216114
	abnormal platelet activation	J:216114
	decreased cerebral infarct size	J:216114
	decreased susceptibility to induced thrombosis	J:216114
	decreased susceptibility to ischemic brain injury	J:216114
	normal homeostasis/metabolism phenotype	J:216114
Pld2^tm1.1Gdp/Pld2⁺ Tg(APPSWE)2576Kha/0 involves: 129X1/SvJ * C57BL/6 * SJL	normal behavior/neurological phenotype	J:166741
	enhanced contextual conditioning behavior	J:166741
Pld2^tm1.1Gdp/Pld2^tm1.1Gdp Tg(APPSWE)2576Kha/0 involves: 129X1/SvJ * C57BL/6 * SJL	abnormal lipid level	J:166741
	abnormal synapse morphology	J:166741
	normal behavior/neurological phenotype	J:166741
	enhanced contextual conditioning behavior	J:166741

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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