About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Neurog3
neurogenin 3
MGI:893591
56 phenotypes from 7 alleles in 9 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Neurog3tm1(EGFP)Khk/Neurog3tm1(EGFP)Khk
involves: 129S6/SvEvTac * C57BL/6 		abnormal pancreatic alpha cell morphology J:77398
abnormal pancreatic beta cell morphology J:77398
abnormal pancreatic delta cell morphology J:77398
disorganized stomach mucosa J:77398
increased stomach mucosa thickness J:77398
regional gastric metaplasia J:77398
small stomach J:77398
Neurog3tm1.1(cre/ERT)Ggu/Neurog3+
involves: 129S6/SvEvTac 		impaired glucose tolerance J:150074
Neurog3tm1.1Ggr/Neurog3tm1.1Ggr
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 		no abnormal phenotype detected J:93570
Neurog3tm1Fgu/Neurog3tm1Fgu
involves: 129S1/Sv * 129X1/SvJ * CD-1 		abnormal pancreatic acinar cell morphology J:60642
absent pancreatic alpha cells J:60642
absent pancreatic beta cells J:60642
absent pancreatic islets J:60642
decreased body weight J:60642
dehydration J:60642
increased circulating glucose level J:60642
increased urine glucose level J:60642
pancreatic acinar cell zymogen granule accumulation J:60642
postnatal lethality, complete penetrance J:60642
Neurog3tm1Fgu/Neurog3tm3.1Ggr
Tg(Vil1-cre)20Syr/0
involves: 129S2/SvPas * C57BL/6 * CD-1 * DBA/2 * SJL 		abnormal abdominal fat pad morphology J:161480
abnormal intestinal enteroendocrine cell morphology J:161480
abnormal intestinal goblet cell morphology J:161480
abnormal intestinal lipid absorption J:161480
abnormal intestinal transit time J:161480
abnormal intestine development J:161480
abnormal large intestine morphology J:161480
abnormal pancreatic islet morphology J:161480
abnormal small intestinal crypt cell proliferation J:161480
abnormal small intestinal microvillus morphology J:161480
abnormal small intestinal villus morphology J:161480
abnormal small intestine crypts of Lieberkuhn morphology J:161480
decreased birth weight J:161480
decreased body mass index J:161480
decreased body size J:161480
decreased circulating cholesterol level J:161480
decreased circulating glucose level J:161480
decreased circulating HDL cholesterol level J:161480
decreased circulating serum albumin level J:161480
decreased circulating triglyceride level J:161480
decreased small intestinal microvillus size J:161480
decreased total body fat amount J:161480
diarrhea J:161480
improved glucose tolerance J:161480
increased blood urea nitrogen level J:161480
increased circulating bicarbonate level J:161480
increased defecation amount J:161480
increased insulin sensitivity J:161480
increased lean body mass J:161480
postnatal growth retardation J:161480
postnatal lethality, incomplete penetrance J:161480
small pancreatic islets J:161480
steatorrhea J:161480
Neurog3tm1Heed/Neurog3tm1Heed
Not Specified 		abnormal endocrine pancreas morphology J:147764
Neurog3tm3.1Ggr/Neurog3tm3.1Ggr
involves: 129S2/SvPas * C57BL/6 * CD-1 * SJL 		no abnormal phenotype detected J:161480
Neurog3tm3.1Ggr/Neurog3tm3.1Ggr
Tg(CDX2-cre)101Erf/0
involves: 129S2/SvPas * C57BL/6J * SJL/J 		decreased enteroendocrine cell number J:285572
normal digestive/alimentary phenotype J:285572
Neurog3tm3.1Ggr/Neurog3tm3.1Ggr
Tg(Vil1-cre)20Syr/0
involves: 129S2/SvPas * C57BL/6 * CD-1 * DBA/2 * SJL 		abnormal abdominal fat pad morphology J:161480
abnormal intestinal enteroendocrine cell morphology J:161480
abnormal intestinal goblet cell morphology J:161480
abnormal intestinal lipid absorption J:161480
abnormal intestinal transit time J:161480
abnormal intestine development J:161480
abnormal large intestine morphology J:161480
abnormal pancreatic islet morphology J:161480
abnormal small intestinal crypt cell proliferation J:161480
abnormal small intestinal microvillus morphology J:161480
abnormal small intestinal villus morphology J:161480
abnormal small intestine crypts of Lieberkuhn morphology J:161480
decreased birth weight J:161480
decreased body mass index J:161480
decreased body size J:161480
decreased circulating cholesterol level J:161480
decreased circulating glucose level J:161480
decreased circulating HDL cholesterol level J:161480
decreased circulating serum albumin level J:161480
decreased circulating triglyceride level J:161480
decreased small intestinal microvillus size J:161480
decreased total body fat amount J:161480
diarrhea J:161480
improved glucose tolerance J:161480
increased blood urea nitrogen level J:161480
increased circulating bicarbonate level J:161480
increased defecation amount J:161480
increased insulin sensitivity J:161480
increased lean body mass J:161480
postnatal growth retardation J:161480
postnatal lethality, incomplete penetrance J:161480
small pancreatic islets J:161480
steatorrhea J:161480
Tg(Pdx1-Neurog3)1Heed/?
involves: C57BL/6 * CBA 		abnormal pancreas development J:57072
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory