Crhr2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Crhr2
corticotropin releasing hormone receptor 2
MGI:894312

31 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Crhr2^tm1Jsp/Crhr2⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	normal behavior/neurological phenotype	J:61485
	normal homeostasis/metabolism phenotype	J:61485
	increased anxiety-related response	J:61485
Crhr2^tm1Jsp/Crhr2^tm1Jsp involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal vascular permeability	J:61485
	normal behavior/neurological phenotype	J:61485
	normal hearing/vestibular/ear phenotype	J:61485
	normal homeostasis/metabolism phenotype	J:61485
	increased anxiety-related response	J:61485
	normal vision/eye phenotype	J:61485
Crhr2^tm1Klee/Crhr2^tm1Klee involves: 129S4/SvJae * C57BL/6	abnormal adipose tissue physiology	J:83683
	abnormal blood vessel morphology	J:76864
	abnormal food intake	J:61484, J:83683
	abnormal glucose homeostasis	J:83683
	abnormal hormone level	J:61484
	abnormal systemic arterial blood pressure	J:61484
	abnormal white fat cell morphology	J:83683
	behavioral despair	J:84341
	decreased brown fat cell size	J:83683
	decreased circulating cholesterol level	J:83683
	decreased circulating free fatty acids level	J:83683
	decreased circulating triglyceride level	J:83683
	decreased total body fat amount	J:83683
	decreased vertical activity	J:83683
	normal endocrine/exocrine gland phenotype	J:61484
	normal homeostasis/metabolism phenotype	J:83683
	hypertension	J:76864
	increased angiogenesis	J:76864
	increased anxiety-related response	J:61484
	increased insulin sensitivity	J:83683
Crhr2^tm1Mpsp/Crhr2^tm1Mpsp involves: 129X1/SvJ	abnormal social investigation	J:161776
Crhr2^tm1Mpsp/Crhr2^tm1Mpsp involves: 129X1/SvJ * C57BL/6J	abnormal eating behavior	J:61510, J:88769
	abnormal hormone level	J:61510
	abnormal myocardial fiber physiology	J:61510
	normal behavior/neurological phenotype	J:61510, J:88769
	normal cardiovascular system phenotype	J:61510
	decreased grooming behavior	J:61510
	normal immune system phenotype	J:61510
	increased systemic arterial blood pressure	J:61510

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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