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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ebf2
early B cell factor 2
MGI:894332
70 phenotypes from 9 alleles in 10 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ebf2em1(IMPC)Mbp/Ebf2+
C57BL/6N-Ebf2em1(IMPC)Mbp/MbpMmucd 		abnormal brain morphology J:211773
abnormal kidney morphology J:211773
abnormal liver morphology J:211773
abnormal retina morphology J:211773
abnormal skin morphology J:211773
abnormal spleen morphology J:211773
abnormal vitreous body morphology J:211773
enlarged heart J:211773
enlarged kidney J:211773
enlarged seminal vesicle J:211773
enlarged spleen J:211773
impaired glucose tolerance J:211773
no spontaneous movement J:211773
shortened ST segment J:211773
small kidney J:211773
small spleen J:211773
small uterus J:211773
Ebf2em1(IMPC)Mbp/Ebf2em1(IMPC)Mbp
C57BL/6N-Ebf2em1(IMPC)Mbp/MbpMmucd 		abnormal blood vessel morphology J:211773
abnormal facial morphology J:211773
abnormal head shape J:211773
abnormal placenta morphology J:211773
abnormal placenta vasculature J:211773
female infertility J:211773
no spontaneous movement J:211773
preweaning lethality, incomplete penetrance J:211773
Ebf2tm1.1Ggc/Ebf2tm1.1Ggc
involves: 129S2/SvPas * C57BL/6J 		abnormal bone structure J:104946
abnormal fat cell morphology J:104946
abnormal long bone epiphyseal plate morphology J:104946
abnormal long bone morphology J:104946
abnormal trabecular bone morphology J:104946
decreased body weight J:104946
decreased bone mineral density J:104946
decreased bone mineral density of femur J:104946
decreased bone strength J:104946
decreased femur compact bone thickness J:104946
postnatal growth retardation J:104946
short tibia J:104946
Ebf2tm1.1Ggc/Ebf2tm1.1Ggc
involves: 129S2/SvPas * C57BL/6J * FVB/N 		abnormal cerebellum anterior vermis morphology J:110576
abnormal cerebellum morphology J:110576
decreased Purkinje cell number J:110576
small cerebellum J:110576
Ebf2tm1Ddr/Ebf2tm1Ddr
129S2/SvPas-Ebf2tm1Ddr 		abnormal neurite morphology J:173959
decreased neuron number J:173959
narcolepsy J:173959
Ebf2tm1Ggc/Ebf2tm1Ggc
either: (involves: 129S2/SvPas * 129X1/SvJ) or (involves: 129S2/SvPas * C57BL/6J) 		abnormal cerebellum morphology J:80220
abnormal epididymis morphology J:80220
abnormal fertility/fecundity J:80220
abnormal gait J:80220
abnormal hypothalamus morphology J:80220
abnormal hypothalamus secretion J:80220
abnormal ovary size J:80220
abnormal reproductive system morphology J:80220
abnormal sciatic nerve morphology J:80220
abnormal seminiferous tubule morphology J:80220
abnormal testis morphology J:80220
decreased body weight J:80220
decreased nerve conduction velocity J:80220
female infertility J:80220
hunched posture J:80220
impaired coordination J:80220
male infertility J:80220
postnatal growth retardation J:80220
testis hypoplasia J:80220
Ebf2tm1Reed/Ebf2tm1Reed
involves: 129S1/Sv * 129X1/SvJ 		abnormal olfactory bulb morphology J:88585
abnormal olfactory neuron innervation pattern J:88585
abnormal sexual interaction J:88585
postnatal lethality, incomplete penetrance J:88585
small olfactory bulb J:88585
Ebf2tm2(Zfp423)Reed/Ebf2+
Omptm4(cre)Mom/Omp+
involves: 129 * 129P2/OlaHsd * C57BL/10J 		abnormal olfactory epithelium morphology J:190934
abnormal olfactory sensory neuron morphology J:190934
impaired neuron differentiation J:190934
Ebf2tm2(Zfp423)Reed/Ebf2+
Omptm4(cre)Mom/Omp+
involves: 129P2/OlaHsd 		abnormal olfactory sensory neuron morphology J:122275
Ebf2tm2(Zfp423)Reed/Ebf2tm2(Zfp423)Reed
Not Specified 		no abnormal phenotype detected J:122275
Ebf2tm2.1(Zfp423)Reed/Ebf2+
involves: 129 * C57BL/10J 		abnormal olfactory epithelium morphology J:190934
abnormal olfactory sensory neuron morphology J:190934
impaired neuron differentiation J:190934
Ebf2tm2.1(Zfp423)Reed/Ebf2+
Not Specified 		abnormal olfactory bulb morphology J:122275
abnormal olfactory epithelium morphology J:122275
abnormal olfactory nerve morphology J:122275
abnormal olfactory sensory neuron morphology J:122275
decreased body size J:122275
Ebf2tm3(Zfp423*)Reed/Ebf2+
Omptm4(cre)Mom/Omp+
involves: 129 * 129P2/OlaHsd * C57BL/10J 		normal nervous system phenotype J:190934
Ebf2tm3.1(Zfp423*)Reed/Ebf2+
involves: 129 * C57BL/10J 		normal nervous system phenotype J:190934
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory